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magnoliapharm3
pharm test 3
| Question | Answer |
|---|---|
| what does alcohol do when combined with barbituates | CNS depression |
| first choice for seizures | valproic acid |
| drug choice for status epilepticus | diazepam |
| first choice drugs for anziety | benzodiazepines |
| what antianxiety drug is nonsedating and non habitforming | buspirone |
| diazepam, larzepam, alprazolam, clonazepam, chlordiazepoxide, | benzos |
| drug used to reduce pts memory of painful procedures not recquiring general ansth | midazolam |
| used to reverse benzo effects | flumazenil |
| drug of choice for tx of mania | lithium |
| serum levels for lithium should be | 0.6-1.2 MeQ/L |
| antidote for heprain | protamine sulfate |
| warfarin toxicity treatment | vitamin K |
| desmopressin, aminocaproic acid | antifibrinolytic, prevents lysis of fibrin, keep clot longer, excessive bleeding tx |
| streptokinase, alteplase | lys clots |
| capsicum pepper, garlic, ginger, gingko, ginseng, feverfew | herbs interact with warfarin, increased bleeding may occur |
| three properties of nsaids | analgesic and antiinflammatory, antipyretic, antirheumatic |
| most widely used drug in the world | salicylates( asprin) |
| moa for allopurinol | reduce production of uric acid |
| moa for colchicine | reduces inflammatory response to teh deposits of urate crystals in joint tissue |
| probenecid, sulfinpyrazone, moa | increase excretion of uric acid in the urine |
| misoprostol | used to reduce dangerous effects of gi bleeding from nsaids |
| salicylate toxicity indications | adults-tinnitus and hearing loss, children-hyperventilation, CNS effecs dizziness |
| serum levels for salicylate toxicity | levels exceed 40 to 60 mg/dl |
| auranofin | 25% gold, oral |
| reyes syndrome | salicylates not to be given to children under ate 18 beacause of |
| OPIOD analgesic used to treat diarrhea | paregoric |
| opiate reversal drugs | naloxone, naltrexone |
| true or false acetamenophen has little or no antiinflammatory effects | TRUE |
| reccommended antidote to acetamenophen toxicity | acetylcysteine regimen |
| maximum daily dose of acetamenophen | 4000 mg per day |
| withold dose of opiods if respiratory rate drops below what | 12 bpm |
| what to use with IV phenytoin | normal saline only, may precipitate |
| hdl level for positive risk factor for CHD | less than 35 mg/dl |
| how long to try diet and excercise before starting antilipemics | 6 months and found to fail before drug therapy |
| HMG-CoA reductase inhibitors | statins |
| hmg-coa does what | used by the liver to produce cholesterol |
| first line drug for ypercholesterolemia | statins |
| adverse effects of statins | rhabdomyolysis |
| bile acid sequestrants | cholestyramine |
| adverse effect of niacin | flushing, pruritus, gi distress |
| fibric acid derivatives | gemfibrozil, fenofibrate |
| adverse effects of fibric acid derivates | increased risk of gall stones |
| main effect of parkinsons | destruction of substantia nigra which produces dopamine |
| on off phenomenon occurs with what drug | levodopa |
| drug that does not induce the cheese effect if 10mg or less is used | selegiline, selective MAO-B inhibitor |
| cheese effect | MAOIs are combined with foods high in tyramine and results in hypertension, cheese, red wine , beer , yogurt |
| used for flu A and treatment of parkinsons by causing relase of dopamine and preventing the reuptake of dopamine | amantadine |
| tolcapone, entacapone | COMT inhibitors, the enzyme responsible for breakdown of levodopa |
| bromocriptine | directly stimulate the dopamine receptors |
| ropinirole | dopamine agonist, used for PD and restless leg syndrome |
| tolcapone can cause what adverse effect | liver failure |
| last drug used in treatment of PD | tolcapone |
| benztroiine mesylate, trihexyphenidyl, biperiden, procylclidine | anticholinergics used for pd |
| drug the reverses effects of levodopa | pyridoxine |
| what foods should people being tx for PD avoid | foods high in vitamin B6 |
| levodopa and MAOIs taken together can cause what | hypertensive crisis |
| what can levodopa due to patients urine and sweat | darken them |
| what drugs cause sleep | hypnotics |
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