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Ch. 12 Musculoskele

DMARDs IFU: Rheumatoid Arthritis (RA) MOA: Slow RA progression by using immune cell activities
Antigout Agents IFU: Gouty Arthritis MOA: Interferes w/ white blood cells to reduce uric acid
Inflammation Result of tissue injury Heat, Pain, Tenderness
NSAIDs IFU: Arthritis, Inflammation and Pain MOA: Inhibit postaglandin, to prevent inflammation
Acetylcholinesterase Inhibitors IFU: Myasthenia gravis MOA: Block acetycholine allow muscle tissue to contract normally
Ailments that originate in the brain Cerebral palsy Stroke Multiple sclerosis
Fibromyalgia Disorder of chronic pain in muscles and soft tissue surrounding joints
Endocrine system Controls minerals in the skeletal system. Thyroid produces calcitonin: allows calcium to remain in bone
Osteoarthritis Erosion of bone where bones meet at the joint
Rheumatoid arthritis Joints affected by inflammation caused by negative immune system reaction Treatment: NSAIDs
Disease-Modifying Anti-Rheumatic Drugs (DMARDs) Used in rheumatoid arthritis when other drugs ineffective Suppresses the autoimmune response Also suppresses immunity systemically
Phantom Limb Pain Comes from brain and spinal cord does not recognize absence of limb Treated w/: Antidepressants, Anticonvulsants, and Narcotics
(COX-2) Inhibitors Decrease the production of prostaglandins that cause pain and inflammation
Paget’s disease Chronic disease that enlarges the bone Resorbs bone excessively, new bone weak and fragile
Gout Arthritis caused by build-up of uric acid in the joints
Abnormal Calcium Levels Treated with Calcium and Vitamin D supplements
Created by: itsefiat



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