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Ch. 12 Musculoskele
Question | Answer |
---|---|
DMARDs | IFU: Rheumatoid Arthritis (RA) MOA: Slow RA progression by using immune cell activities |
Antigout Agents | IFU: Gouty Arthritis MOA: Interferes w/ white blood cells to reduce uric acid |
Inflammation | Result of tissue injury Heat, Pain, Tenderness |
NSAIDs | IFU: Arthritis, Inflammation and Pain MOA: Inhibit postaglandin, to prevent inflammation |
Acetylcholinesterase Inhibitors | IFU: Myasthenia gravis MOA: Block acetycholine allow muscle tissue to contract normally |
Ailments that originate in the brain | Cerebral palsy Stroke Multiple sclerosis |
Fibromyalgia | Disorder of chronic pain in muscles and soft tissue surrounding joints |
Endocrine system | Controls minerals in the skeletal system. Thyroid produces calcitonin: allows calcium to remain in bone |
Osteoarthritis | Erosion of bone where bones meet at the joint |
Rheumatoid arthritis | Joints affected by inflammation caused by negative immune system reaction Treatment: NSAIDs |
Disease-Modifying Anti-Rheumatic Drugs (DMARDs) | Used in rheumatoid arthritis when other drugs ineffective Suppresses the autoimmune response Also suppresses immunity systemically |
Phantom Limb Pain | Comes from brain and spinal cord does not recognize absence of limb Treated w/: Antidepressants, Anticonvulsants, and Narcotics |
(COX-2) Inhibitors | Decrease the production of prostaglandins that cause pain and inflammation |
Paget’s disease | Chronic disease that enlarges the bone Resorbs bone excessively, new bone weak and fragile |
Gout | Arthritis caused by build-up of uric acid in the joints |
Abnormal Calcium Levels | Treated with Calcium and Vitamin D supplements |