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Chapter 10
Analgesic Drugs
Question | Answer |
---|---|
Medications that relieve pain without causing loss of consciousness | Analgesics |
An unpleasant sensory and emotional experience associated with actual or potential tissue damage | Pain |
Pain results from stimulation of sensory nerve fibers called? | Nociception |
Level of stimulus needed to produce the perception of pain | Pain Threshold |
The amount of pain a person can endure without it interfering with normal function | Pain Tolerance |
Sudden onset usually subsides once treated | Acute pain |
Assist primary drugs in relieving pain | NSAIDs (non steroidal antiflamitory drugs) |
Examples of adjuvant drugs for neuropathic pain | Amitripyline (anti depressant) Gabapentin( anticonvulsants) |
Assist primary drugs in relieving pain | Adjuvant drugs |
Three step analgesic ladder | - nonopioids with or without adjuvant medication -opioids with or without nonopiods/ with or without adjuvants -opioids for moderate to severe pain (ex Nicodin Percocet) |
Synthetic drugs that bind to the opiate receptors to relieve pain | Opioid drugs |
Name the mild agonists opioids (2) | codeine, hydrocodone |
Name the strong agonists opioids (7) | morphine, hydromorphone, oxycodone, meperidine, fentanyl, methadone |
When drug reaches a maximum analgesic effect and does not improve, even with a higher dosage it is called | Opioid ceiling effect |
Ability provide equivalent pain relief by calculating dosage of different drugs or routes of administration that provide comparable analgesia | Equianalgesa |
Opioids could also be used to treat..... | cough center suppression diarrhea balanced anesthesia |
Known drug allergy for Opioids | severe asthma |
Opioid adverse effects | CNS depression, Nausea, vomiting, urinary retention, diaphoresis, pupil constriction (miosis), constipation, itching |
What would you give a patient that has overdose on a opioid? | Naloxone or Naltrexone |
Opioid Interactions | alcohol, antihistamines, barbiturates, benzodiazepines, monoamine oxidase inhibitors |