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antiviral drugs
| Question | Answer |
|---|---|
| Who are immunocompromised clients | - cancer clients - clients with organ transplants - clients with AIDS |
| how do antivirals kill or suppress viruses | - Destroying virions - Inhibiting their ability to replicate |
| what are types of drugs that destroy virions | - disinfectants - immunoglobulins |
| what types of viruses are controlled by antivirals | - Cytomegalovirus (CMV) - Hepatitis viruses (A, B, C) - Herpes viruses - Human immunodeficiency virus (HIV) - Influenza viruses (the flu) - Respiratory syncytial virus (RSV) |
| what are opportunistic infections | - infections that would not normally harm an immunocompetent clients |
| what are antiviral drugs used for | - treatment of infections that caused by viruses that are not HIV |
| what are Antiretroviral drugs used for | - Used to treat infections caused by HIV, the virus that causes AIDS |
| what are the types of Herpes simplex viruses | - HSV-1 (oral herpes) - HSV-2 (genital herpes) |
| what are the types of Varicella zoster virus | - Chickenpox - Shingles |
| what are the contraindications for antivirals | - Pregnant or lactating women - Children younger than 12 months of age - Patients with an eczematic rash - Patients with severely compromised kidney function Pre-existing hemoglobinopathies |
| what are the common adverse effects of antivirals | - insomnia - nervousness - nausea |
| what are the commonly used antivirals | - acyclovir - ribavirin |
| what is the common name for acylovir | - zovirax |
| what is the common names for ribavirin | - pegetron - copegus |
| what is the commonly used Neuraminidase Inhibitors | - oseltamivir |
| what is the common name for oseltamivir | - tamiflu |
| what is oseltamivir used for | - influenza type a and b |
| what is the adverse effects of oseltamivir | - nausea - vomiting |
| when should the use of neuraminidase inhibitors | - within 2 days of symptom onset |
| what is the mechanism of action for fusion inhibitors | - Inhibit viral fusion, preventing viral replication |
| what is the mechanism of action for Protease inhibitors (PIs) | - Inhibit the protease retroviral enzyme, preventing viral replication |
| what is the mechanism of action for Reverse transcriptase inhibitors (RTIs) | - Block activity of the enzyme reverse transcriptase, preventing production of new viral DNA |
| what is the commonly used protease inhibitor | - nelfinavir mesylate (Viracept) |
| What is the goal in HIV treatment | - to find the regimen that will best control the infection with a tolerable adverse-effect profile |