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Stack #3093612
transmucosal dosage forms
dosage form | advantages | disadvantages |
---|---|---|
Buccal | Rapid onset of action, fewer side effects | Unpleasant taste, local mouth irritation, “dose dumping” if directions not followed |
Ophthalmics, otics, and nasal sprays/solutions | Fast onset of action, localized therapeutic effect | |
Nasal solutions/sprays | Fast onset of action, localized therapeutic effect | Some have systemic side effects |
Suppositories and solutions | Depending on the medication, can be used for either local or systemic action | Patient inconvenience and discomfort, premature expulsion of the suppository, irregular drug absorption |
Sublingual | Rapid onset of action | Short duration of action |