Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

CAD / Lytic Drugs


Antithrombotics include: Fibrinolytics, anticoagulants, antiplatelet drugs
Use of fibrinolytics STEMI only
Anticoagulants: acute & chronic Acute: UFH, LMWH, DTIs; chronic: warfarin
UFH vs LMWH re: inactivating thrombin UFH > LMWH
Beta blockers AEs Hypotension; Decrease HR, heart block; May worsen HF symptoms; CNS (fatigue, malaise, depression); Bronchospasm (use ß1 selective agents)
Irreversibly binds to ADP receptor on platelets; Full reversal requires removal of plts Clopidogrel
Fibrinolytics: absolute CI Prior hemorrhagic CVA; any cerebrovascular events < 1 year; active internal bleeding; Known intracranial neoplasm; suspected aortic dissection
Fibrinolytics: relative CI BP > 180/110; Use of anticoags w/ INR > 2; Noncompressible vascular punctures; Prolonged CPR (> 10 minutes); PG or Menstruation; Trauma < 2-4 weeks prior; Major surgery < 3 weeks prior
UFH: main risk = bleeding
UFH: used for: Both STEMI and NSTEMI
ATPIII/heparin has greatest effect on: Factor II (thrombin)
Can use to monitor LMWH Factor Xa
UFH/LMWH adverse effects Bleeding, HIT, osteoporosis
UFH vs LMWH: which inhibited by PF4 (thus limited effect vs ACS)? UFH
UFH vs LMWH: which requires renal dose adjustment? LMWH
Tx for catheter thrombosis during PCI Fondiparinux
Bivalirudin is used in STEMI in place of: UFH / LMWH
Add warfarin for: pts w/ USA or NSTEMI w/anticoag indication (to maintain INR 2.0-3.0)
Clopidogrel dosing usu loading & maint doses
Clopidogrel AEs Bleeding; Thrombocytopenia; Leukopenia; TTP
Which patients get clopidogrel? All STEMI/NSTEMI (2-4 wks to 1 yr)
Which patients get GP IIb/IIIa inhibitors? STEMI pts going for PCI
GP IIb/IIIa inhibitors are not recommended if: PCI is not planned
ACS mgmt = MONA (morphine, O2, NTG, ASA or antiplatelet tx); BB, ACEI, CCB, statin, anticoag (STEMI: fibrinolytics: streptokinase / alteplase); Surg: PTCA
Examples (5) of direct thrombin inhibitors dabigatran (Pradaxa), desirudin, lepirudin, argatroban, bivalidrudin
Xa inhibitors Fondaparinux (Arixtra): DVT/PE. Rivaroxaban (Xarelto): nonvalvular A-fib. Apixaban (Xarelto): DVT/PE
Created by: Abarnard



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards