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Module 1
Pharmacology module 1
Term | Definition |
---|---|
Absorption | Process by which a drug is taken into the body and moves from the site of administration into the blood. |
Adverse effect | Undesired, potentially harmful side effects of drugs. |
Agonist | Drug molecule that binds to a receptor and causes a response |
Antagonist | Drug that binds to specific receptor sites and prevents other medications from binding to these same sites, reversing or not allowing them to have an effect. |
Bioavailability | The extent to which an administered amount of a drug reaches the site of action and is available to produce its effects. |
Biotechnology | Concepts of genetic engineering and recombinant DNA technology. |
Biotransformation | Process of changing the chemical composition of a drug from lipid-soluble molecules into water-soluble molecules that can be more easily excreted; usually takes place in the liver; also known as drug metabolism. |
Bolus | Entire dose of medication given all at once |
Contraindication | Condition when the use of a given medication should be avoided |
Distribution | Process in which the circulatory system transports a drug throughout the body and drug molecules eventually diffuse out of the bloodstream to the site of action. |
Duration | Time between onset and disappearance of drug effects. |
Emulsion | Medication contained in a mixture of water and oil bound together with an emulsifier |
Enteral | Pertaining to the intestinal tract. |
Excretion | Process of elimination of drug molecules from the body; usually by the urinary system. |
Hypersensitivity | Allergic response resulting from previous exposure to the drug or a similar drug; a type of adverse effect to a drug. |
Idiosyncratic effect | Rare and unpredictable adverse effects of some drugs on individuals in which the mechanism of the effect may not be known or clearly understood. |
Indication | Reason a medication is used to treat a condition. |
Local effect | Medication acts at the site of application. |
Onset | Time between administration of a drug and the first appearance of effects. |
Parenteral | Pertaining to any drug administration route other than the intestinal tract. |
Pharmacodynamics | Study of how drug actions affect the body. |
Pharmacokinetics | Study of how the body processes drugs |
Plasma protein binding | Process in which some drug molecules attach to proteins (albumins and globulins) contained in blood plasma |
Reconstituted | Mixing a powder with a liquid to form a solution. |
Side effect | Predictable but unintended effect of a drug. |
Solubility | Characteristic indicating how easily a drug can be dissolved in a fluid. |
Solution | Mixture of drug particles fully dissolved in a liquid. |
Suspension | Mixture of undissolved drug particles floating in a liquid |
Synergist | Drug that enhances the effect of another drug. |
Systemic effect | Medication acts throughout the body. |
Topical | Pertaining to a surface; drug administration route applied to the skin or a mucous membrane–lined cavity. |
Controlled substances | Medication with the potential to be misused or abused, controlled by the Drug Enforcement Administration, and given a classification/schedule. |
Narcotics | Term for a controlled substance that depresses the central nervous system for pain control and has the potential to become habit-forming |
DEA | Drug Enforcement Administration, part of the Department of Justice, established to enforce the Controlled Substances Act. |
FDA | Food and Drug Administration. Agency within the Department of Health and Human Services that regulates the pharmaceutical industry. |
The Joint Commission | Organization that evaluates and accredits health care organizations and programs in the United States. |
OTC | Term used for over-the-counter medication that does not require a prescription. |
PDR | Physicians’ Desk Reference. Reference that provides information on medications used in medical and surgical practice |
USP-NF | United States Pharmacopeia and National Formulary. Two different official national lists of approved medications |