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Week 1 Ch 1 and 2
General Terms
| Term | Definition |
|---|---|
| Absorption | when something is absorbed by another |
| Adverse effect | potentially harmful side effects from drugs -nausea, vomiting, drug toxicity |
| agonist | initiates a physiological response when it is combined with a receptor |
| antagonist | bind to receptors blocking agonists, alters target site |
| Bio availability | degree of the which the molecule (drug) reached action site to exert effectiveness -acid-base balance affect effectiveness |
| biotechnology | genetic engineering, allows scientists to produce proteins from bacteria |
| biotransformation | when a drugs chemical composition is changed by metabolism |
| bolus | administration of medication , given at specific time |
| contraindiction | a situation when a drug, surgery or procedure should be avoided due to potential harm to patient |
| distribution | when drug molecules diffuse out of blood stream and reach site of action |
| duration | time between onset and disappearance of a drugs effect |
| emulsion | medication is in a mixture of water and oil which is all bound by a emulsifier |
| enteral | route of administration, medication is taken in the GI tract |
| excretion | eliminates medications from body |
| hypersensitivity | adverse effect which happens due to previous exposure to the drug/ similar drug |
| idiosyncratic effect | unpredictable adverse effects of drugs |
| indication | reason/purpose for giving med. |
| local effect | when topical agents work at site of application |
| onset | first appearance of effect |
| parenteral | any route other than digestive tract |
| pharmacodynamics | examines how the drug affects body |
| pharmacokinetics | how the body processes drugs |
| plasma protein binding | refers to degree of how medications attach to proteins that are in the blood |
| reconstituted | powders that are mixed with liquids |
| side effect | predictable/unintended effect from a drug |
| solubility | a drugs ability to be dissolved |
| solution | mixture in which drug particles are fully dissolved (liquid medium) |
| suspension | a suspension where solid, undissolved particles float in liquid |
| synergist | a drug that enhances an affect of another drug |
| systemic effect | when effects occur at a distant site of contact |
| topical | on the skin |
| controlled substances | a drug that is regulated by the government |
| narcotics | a drug/substance that affects mood or behavior , has sleep-inducing properties |
| DEA | The Drug Enforcement Administration: sets standards for controlled substances and enforces the rules |
| FDA | Food and Drug Administration: protects public health. -drugs, biological products, medical devices |
| the joint commission | accredits hospitals and health care institutions |
| OTC | over the counter |
| PDR | Physicians desk reference |
| USP-NF | reference of officially approved drugs |