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Basic Pharmacology

Module 1

absorption process of drug moving from administration site of body into the blood
adverse effect undesired and possibly harmful side effects from a drug
agonist molecule of a drug that binds to a receptor and causes a response
antagonist molecule of a drug that binds to a receptor, preventing other drugs from binding
bioavailability amount of drug that reaches the site of action and causes the effect
biotechnology area of genetic engineering and recombinant DNA technology
biotransformation metabolism of drug in the body; converting drug from lipid-soluble to water-soluble in body for easier excretion
bolus entire dose of medication given at one time
contraindication a condition where the drug should not be taken
distribution circulatory system process that delivers the drug through the bloodstream to the site of action, where the drug diffuses out
duration period of time from when medication effects begin to when the medication effects end
emulsion medication in a mix of oil and water which is bound together with an emulsifier
enteral regarding the intestinal tract
excretion elimination process of the drug through the body; usually completed by the urinary system
hypersensitivity allergic response to a drug or a similar drug resulting from previous exposure; a type of adverse effect
idiosyncratic effect rare/unpredictable adverse effect for which the cause is unknown or not understood
indication reason for medication usage
local effect medication acts at site of administration
onset amount of time between administration of drug and the time of effects
parenteral any route of administration other than intestinal
pharmacodynamics study of how drug actions affect the body
pharmacokinetics study of how body processes drugs
plasma protein binding process in which some drug molecules attach to proteins in blood plasma (i.e. albumins, globulins)
reconstituted a solution formed from a powder and liquid
side effect unintended but predictable effect of a drug
solubility how easily a drug dissolves in a fluid
solution mixture of drug that is completely dissolved in a liquid
suspension mixture of drug that is undissolved and floating in a liquid
synergist drug that enhances effects of another drug
systemic effect medication acts throughout the body
topical drug administration to skin or mucous-membrane lined cavity
controlled substances drug with potential for misuse or abuse; controlled by DEA; given a classification/schedule
narcotics controlled substance that depresses CNS; used for pain control
DEA Drug Enforcement Agency; part of Dept of Justice; enforces Controlled Substances Act
FDA Food & Drug Administration; part of Dept of Health & Human Services; regulates pharmaceutical industry
The Joint Commission evaluates and accredits healthcare organizations and programs in US
OTC Over The Counter; medication that does not require a prescription
PDR Physicians; Desk Reference; source of information on medications used in medicine and surgery
USP-NF United States Pharmacopeia & National Formulary; 2 different national lists of approved medications
Created by: kluing



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