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Basic Pharmacology
Module 1
| Term | Definition |
|---|---|
| absorption | process of drug moving from administration site of body into the blood |
| adverse effect | undesired and possibly harmful side effects from a drug |
| agonist | molecule of a drug that binds to a receptor and causes a response |
| antagonist | molecule of a drug that binds to a receptor, preventing other drugs from binding |
| bioavailability | amount of drug that reaches the site of action and causes the effect |
| biotechnology | area of genetic engineering and recombinant DNA technology |
| biotransformation | metabolism of drug in the body; converting drug from lipid-soluble to water-soluble in body for easier excretion |
| bolus | entire dose of medication given at one time |
| contraindication | a condition where the drug should not be taken |
| distribution | circulatory system process that delivers the drug through the bloodstream to the site of action, where the drug diffuses out |
| duration | period of time from when medication effects begin to when the medication effects end |
| emulsion | medication in a mix of oil and water which is bound together with an emulsifier |
| enteral | regarding the intestinal tract |
| excretion | elimination process of the drug through the body; usually completed by the urinary system |
| hypersensitivity | allergic response to a drug or a similar drug resulting from previous exposure; a type of adverse effect |
| idiosyncratic effect | rare/unpredictable adverse effect for which the cause is unknown or not understood |
| indication | reason for medication usage |
| local effect | medication acts at site of administration |
| onset | amount of time between administration of drug and the time of effects |
| parenteral | any route of administration other than intestinal |
| pharmacodynamics | study of how drug actions affect the body |
| pharmacokinetics | study of how body processes drugs |
| plasma protein binding | process in which some drug molecules attach to proteins in blood plasma (i.e. albumins, globulins) |
| reconstituted | a solution formed from a powder and liquid |
| side effect | unintended but predictable effect of a drug |
| solubility | how easily a drug dissolves in a fluid |
| solution | mixture of drug that is completely dissolved in a liquid |
| suspension | mixture of drug that is undissolved and floating in a liquid |
| synergist | drug that enhances effects of another drug |
| systemic effect | medication acts throughout the body |
| topical | drug administration to skin or mucous-membrane lined cavity |
| controlled substances | drug with potential for misuse or abuse; controlled by DEA; given a classification/schedule |
| narcotics | controlled substance that depresses CNS; used for pain control |
| DEA | Drug Enforcement Agency; part of Dept of Justice; enforces Controlled Substances Act |
| FDA | Food & Drug Administration; part of Dept of Health & Human Services; regulates pharmaceutical industry |
| The Joint Commission | evaluates and accredits healthcare organizations and programs in US |
| OTC | Over The Counter; medication that does not require a prescription |
| PDR | Physicians; Desk Reference; source of information on medications used in medicine and surgery |
| USP-NF | United States Pharmacopeia & National Formulary; 2 different national lists of approved medications |