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Chapter 1: Intro to Respiratory Care Pharmacology

ARDS Acure respiratory distess syndrom- disorder characterized by respiratory insufficiency. May occur as a result from trauma, pneumonia, oxygen toxicity, gram-neg. sepsis, and systemic inflammatory response.
COPD Airflow limitation that is not fully reversible, usually progressive, and associated w/an abnormal inflammatory response of the lung to noxious gases or particles. (Chronic Bronchitis,Emphysema,Asthma,and Bronchiectasis).
Code Name Name assigned by manufacturer to an experimental chemical that shows potential as a drug. ex: SCH1000
CF Cystic Fibrosis: inherited disease of the exocrine glands, affecting the pancreas, respiratory system, and apocrine glands. Symptoms usually during infancy and are characterized by increased electrolytes in sweat, and chronic respiratory infection.
Generic Name Name assigned to a chemical by the USNA council when the chemical appers to have therapeutic use and manufacturer wishes to market the drug.
Pharmacy The preparation and dispensing of drugs
Pharmacognosy The identification of sources of drugs, from plants and animals.
Pharmacogenetics The study of the interrelationship of genetic differences and drug effects
Terapeutics The art of treating disease with drugs
Toxicology Study of toxic substances and their pharmacological actions, including antidotesw and poison control
Each drug has five different names, they are... Chemical, code, official, generic, and Trade/Brand name
Pharmacodynamics The machanisms of drug action by wich a drug molecule causes its effect in the body.
Pharmacokinetics The time course and disposistion of a drug in the body, baseed on its absorption, distribution, metabolism, and elimination.
Pseudomonas aeruginosa Gram-neg. orgnanism, primarily a nosocomial pathogen, causes UTI, URI, Dermatitis, soft tissue infections, bacteremia, bone and joint infections,etc.. Particularly in severely burned or immunosuppressed patients.
RSV Respiratory syncytial virus: Virus that causes the formation of syncytial masses in cells, leads to imflammation of the bronchiles, which may cause respiratory distress in young infants.
Advantages of Aerosolized agents given by inhalation Smaller doses for the same purpose and given systemically, fever and less sever side effects, onset of action is rapid, delivery targeed to respiratory system w/lower systemic bioavailability, painless, relatively safek, can be more convenient.
Antiinfective agents Inhibition or eradication of specific infective agents, such as Pneumocytis carnii, RSV, CF or influenze A and B, antibiotics or antituberculous drugs.
Adrenergic Agernts Relaxation of bronchial smooth muscle and bronchodilation, to reduce airway resistance and to improve ventilatory rates in airway obstruction in COPD'ers.
Anticholinergic Agents Topical vasoconsstriction and decongestion, relaxation of cholinergically induced bronchocontriction to improve ventilatory flow rates in COPD
Mucoactive Agents Modification nof the properties or Respiratory tract mucus, current agents lower viscosity and promote clearance of secreations
Corticosteroids Reduction and control of airway inflammatory response, usually associated w/asthma or with seaonal or chronic rhinitis (URI).
Antiasthmatic Agents Prevention of the onset and development of the asthmatic response, through inhibition of chemical mediators of inflammation
Exogenous Surfactants Approved clinical use is by direct intratracheal instillation, for the purspose of restoring more normal lung compliance in RDS in newborns
Created by: brittanyh1x215