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Oncology II

Common Breast Cancer and Prostate Cancer Hormonal Tx

HERS + pertuzumab: HERS receptor blocker
ER or PR Positive Hormonal therapies: 1- post menopausal: AI ( 5y/r 2- pre menopausal: SERM ( 10yr
Breast Cancer Male - Tamoxifen
Pre menopausal Women with ER or PR + preferred: SERM other option: AI + GnRH blocker
Which hormonal therapies for breast cancer patient? - SERM - AI - CDKI
SERM drugs: - tamoxifen - fluvestrant - Raloxifene - toremifene
AI drugs - Anastrozole - letroazole - exemestane
CDKI drugs - Palbociclib
Which hormonal therapies for prostate cancer patient? - GnRH agonist / blocker - Anti androgen - androgen biosynthesis inhibitor
GnRH blocker degarelix
GnRH agonist - leuprolide - goserelin - histrelin - triptorelin
anti androgen - cicalutamide - flutamide - nilutamide - 2nd generatio--> enzalutamide
Androgen biosynthesis inhibitor abiraterone
GnRH agonist used in breast cancer? leuprolide goserelin
SERM used in men breast cancer tamoxifen
Created by: Smoham38



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