click below
click below
Normal Size Small Size show me how
Oncology II
Common Breast Cancer and Prostate Cancer Hormonal Tx
| Term | Definition |
|---|---|
| HERS + | pertuzumab: HERS receptor blocker |
| ER or PR Positive | Hormonal therapies: 1- post menopausal: AI ( 5y/r 2- pre menopausal: SERM ( 10yr |
| Breast Cancer Male | - Tamoxifen |
| Pre menopausal Women with ER or PR + | preferred: SERM other option: AI + GnRH blocker |
| Which hormonal therapies for breast cancer patient? | - SERM - AI - CDKI |
| SERM drugs: | - tamoxifen - fluvestrant - Raloxifene - toremifene |
| AI drugs | - Anastrozole - letroazole - exemestane |
| CDKI drugs | - Palbociclib |
| Which hormonal therapies for prostate cancer patient? | - GnRH agonist / blocker - Anti androgen - androgen biosynthesis inhibitor |
| GnRH blocker | degarelix |
| GnRH agonist | - leuprolide - goserelin - histrelin - triptorelin |
| anti androgen | - cicalutamide - flutamide - nilutamide - 2nd generatio--> enzalutamide |
| Androgen biosynthesis inhibitor | abiraterone |
| GnRH agonist used in breast cancer? | leuprolide goserelin |
| SERM used in men breast cancer | tamoxifen |