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Chapter 23 questions

Study of how drugs produce their effect on their desired cell and how drugs are processed in the body Pharmacodynamics
The location where the drug will exert its desired action Site of action
Explains how a drug works and produces its desirable or undesirable effect Mechanism of action
Location where the drug binds to the cell Receptor site
Specific type of drug that produces a certain predicted actions Agonist
Type of drug that does not produce or inhibits the desirable effect and blocks cell receptors Antagonist
The degree to which a drug becomes available to tissues after administration Bioavailability
Occurs when a person requires larger doses of a drug to achieve the same effect Tolerance
The body’s response to a drug Desired effect
Indicates that the body’s response to a drug is directly related to the amount taken Dose response curve
The maximal response that the body has to a drug known as the Ceiling
The measurement of strength of the drug that is required Potency
The amount needed to achieve 50% of the maximal response ED50
Time required for plasma serum concentration levels to decrease by one half Half life
Half life is written as T1/2
Length of time in which a drug will continue to have the same degree of effect is know as the Time response curve
The process where the drug is moved from its site of administration into the bloodstream Absorption
What drug bypasses absorption Intravenous
When the dry is moved from the bloodstream to the tissues or receptors Distribution
Movement of a substance across the cell membrane Passive diffusion
Carrier proteins permit specific molecules from passing through certain parts of the cell Facilitated diffusion
Cell engulfs the substance and permits the substance to enter the cell Pinocytosis
The more lipid soluble the drug is the more ______ the drug will be absorbed into the body Quickly
Time is takes the drug to be eliminated from the body Clearance
Process where the drug effects the cell in the body by interacting with receptors can be compared to a _____ and ______ Lock and key
You would use _____________ to find out how drugs are changed in the body from their original form to something the body can use Pharmacokinetics
________ binds directly to the cell membrane and is not absorbed by the body in any way Metamucil
The______ of a drug governs it’s bioavailability Absorption
Some drugs require immediate access to the body’s cells while others survive longer to be effective because of the ___________ of the drug is time restricted Bioavailability
_______ _________ does not require the cell to expend energy Facilitated diffusion
When a chemical binds with a ________ it’s stimulated to either produce or inhibit an action Receptor
For an oral medication to be absorbed into the body it must go through the ____ _______ _______ which is completed the liver First pass process
When serum concentration is less that 3% it is considered To be removed from the body
Many problems related to drug drug interactions occur when antagonistic drug is added to.... A number of other antagonistic drugs
Drug drug interactions may occur because _____________________ healthy people Drug testing is never performed on
____ _________ is more important because drugs that are eliminated more slowly than they are absorbed can cause interactions with other substances Drug clearance
Created by: Mere_a_



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