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Chapter 23 questions
Question | Answer |
---|---|
Study of how drugs produce their effect on their desired cell and how drugs are processed in the body | Pharmacodynamics |
The location where the drug will exert its desired action | Site of action |
Explains how a drug works and produces its desirable or undesirable effect | Mechanism of action |
Location where the drug binds to the cell | Receptor site |
Specific type of drug that produces a certain predicted actions | Agonist |
Type of drug that does not produce or inhibits the desirable effect and blocks cell receptors | Antagonist |
The degree to which a drug becomes available to tissues after administration | Bioavailability |
Occurs when a person requires larger doses of a drug to achieve the same effect | Tolerance |
The body’s response to a drug | Desired effect |
Indicates that the body’s response to a drug is directly related to the amount taken | Dose response curve |
The maximal response that the body has to a drug known as the | Ceiling |
The measurement of strength of the drug that is required | Potency |
The amount needed to achieve 50% of the maximal response | ED50 |
Time required for plasma serum concentration levels to decrease by one half | Half life |
Half life is written as | T1/2 |
Length of time in which a drug will continue to have the same degree of effect is know as the | Time response curve |
The process where the drug is moved from its site of administration into the bloodstream | Absorption |
What drug bypasses absorption | Intravenous |
When the dry is moved from the bloodstream to the tissues or receptors | Distribution |
Movement of a substance across the cell membrane | Passive diffusion |
Carrier proteins permit specific molecules from passing through certain parts of the cell | Facilitated diffusion |
Cell engulfs the substance and permits the substance to enter the cell | Pinocytosis |
The more lipid soluble the drug is the more ______ the drug will be absorbed into the body | Quickly |
Time is takes the drug to be eliminated from the body | Clearance |
Process where the drug effects the cell in the body by interacting with receptors can be compared to a _____ and ______ | Lock and key |
You would use _____________ to find out how drugs are changed in the body from their original form to something the body can use | Pharmacokinetics |
________ binds directly to the cell membrane and is not absorbed by the body in any way | Metamucil |
The______ of a drug governs it’s bioavailability | Absorption |
Some drugs require immediate access to the body’s cells while others survive longer to be effective because of the ___________ of the drug is time restricted | Bioavailability |
_______ _________ does not require the cell to expend energy | Facilitated diffusion |
When a chemical binds with a ________ it’s stimulated to either produce or inhibit an action | Receptor |
For an oral medication to be absorbed into the body it must go through the ____ _______ _______ which is completed the liver | First pass process |
When serum concentration is less that 3% it is considered | To be removed from the body |
Many problems related to drug drug interactions occur when antagonistic drug is added to.... | A number of other antagonistic drugs |
Drug drug interactions may occur because _____________________ healthy people | Drug testing is never performed on |
____ _________ is more important because drugs that are eliminated more slowly than they are absorbed can cause interactions with other substances | Drug clearance |