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DM Clinical Summary

Quick Recap of DM- Clinical Summary

TermDefinition
Which anti DM drugs reduce the A1c the most? Insulin followed by metformin
Which Anti DM drugs increase risk of hypoglycemia the most ? Insulin -- other insulin secretagogues: SU, meglitinides -- Pramlintide with insulin combo
Which anti DM drugs cause WEIGHT GAIN the most? Insulin followed by SU
Which anti DM drugs cause WEIGHT LOSS the most? - SGLT-2 - GLP-1 - pramlintide
Which Anti DM drugs have cardiac compelling effect? - Empagliflozin - liraglutide ( EM LIRA)
Which Anti DM drugs are the cheapest ? - metformin
Which anti DM drugs are C/I if eGFR < 30? - metformin - SGLT-2 inhibitor - exenatide, exenatide extended release - GLYburide
Which anti DM drugs can increases the risk/ exacerbate HF? - TDZs - DDP-4 inhibitor: alogliptin and saxagliptin
Which anti DM drug can cause peripheral neuropathy, ulcer, amputation? - canagliflozin
Which ant DM drugs are not recommended in gastroparesis and GI disorders? - GLP-1 agonist - pramlintide
Which anti DM drugs can causes sulf allergy? SU
Which anti DM drugs should be used in caution in pt with G6PD deficiency? SU
What is the major risk of using metformin? lactic acidosis
Which class/drug can induce hepatotoxicity ? - Alogliptin - TZD ( zone)
which class/drug can induce hypotension/ low BP/ volume depletion and dehydration? SGLT-2 inhibitor
Which class/drug increases the risk of UTI/ genital infection? SGLT-2 2/2 glucose excretion in the urine
Which class/drug can causes HYPER KALEMIA? high K Canagliflozin
which class/drug can causes HYPO KALEMIA? low K insulin
Which drug the long term use of it causes Vit-B12 deficiency?? metformin
which drug can reduce the absorption of fat soluble vitamins ( ADEK) ? colesevelam
Which drug/class can cause Pancreatitis? - DPP-4 inhibitors - GLP-1 agonist
Which drug/class can cause hypersensitivity reactions? - SU - DPP-4
Which drug/class can increase the risk of bladder cancer? dapagliflozin pioglitazone
which drug class can increases the risk of thyroid cancer? GLP-1 agonist except ( byetta) and adlyxin
Created by: Smoham38
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