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Table 10.1

Centrally Acting Muscle Relaxants

GenericBrandDosage FormRoute of AdministrationCommon Dose
Cyclobenzaprine hydrochloride (Flexeril) Tablet, extended-release (ER) capsule Oral Tablet: 5-10 mg 3 times a day ER capsules: 15-30 mg a day
Metaxalone (Skelaxin) Tablet Oral 800 mg 3 times a day
Methocarbamol Robaxin Tablet, injectable solution Oral, IM, IV PO: 750-1,500 mg 3-4 times a day IM/IV: 1,000 mg (maximum infusion rate of 300 mg/min may be repeated every 8 hours as needed)
Orphenadrine citrate Norflex Tablet, ER tablet, injectable solution Oral, IM, IV PO: 100 mg 2 times a day in morning and evening IM/IV: 60 mg, may be repeated every 12 hours as needed
Tizanidine (Zanaflex) (Zanaflex) Tablet, capsule Oral 4-8 mg every 6-8 hours
Baclofen Lioresal Tablet, oral solution, intrathecal (IT) solution Oral, IT PO: 20-80 mg/day in divided doses 3-4 times a day IT: 90-800 mcg/day via continuous infusion pump
Carisoprodol Soma Tablet Oral 250-350 mg 3 times a day and bedtime
Chlorozoxazone Paraflex, Parafon Forte Tablet Oral 250-750 mg 3-4 times a day
Created by: lalorod75



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