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Neuro Drugs
| Term | Definition |
|---|---|
| fluxetine | Increased risk for suicide, serotonin syndrome, hyponatremia 4-6 weeks for effectiveness |
| venlafaxine | GI symptoms, Hyponatremia |
| bupropine hydrochloride | increased risk for suicide, nausea vomiting, weight loss, increased risk for seizures |
| Lithium | GI problems, tremors (Can indicate toxicity) Monitor sodium levels Monitor drug level (0.4-1.4) |
| dantrolene | lightheadedness, fatigue, muscle weakness, diarrhea, hepatic toxicity Monitor Liver Function |
| phenelzine | ortho-hypo, drowsiness, HTN crisis, Cannot have cheese, chocolate, or coffee |
| amitriptyline | drowsiness, sedation, ortho-hypo Encourage long-term use several weeks to feel full effect |
| levodopa-carbidopa | hypotension, orthostatic, dark urine and sweat, dyskinesis, on and off hallucinations, paranoia |
| selegiline | insomnia, B/P issues, HTN crisis, hypotension, oral mucous membranes irritation No food or drink 5 minutes before or after administration |
| pramipexole | GI symptoms, Orthostatic hypotension, dyskinesis, sleep attacks, muscle weakness Monitor CPK (for possible skeletal musce damage) |
| buspirone | Paradoxical effects (Insomnia) Up to a week for therapeutic levels to be reached |
| diazepam | drowsiness, impaired memory, resp depression, tolerance, overdose, vision problems, incontinance Can be addictive; Flumazenil treat O.D. |
| carbamazepine | nystagmus, vision problems, vertigo, ataxia, decreased heart rate, stevens-johnsons syndrome Give HS ,,Begin with lowest dosage |
| phenytoin | nystagmus, skin rash, hirsutism, pronounced gums, purple hands ataxia Blood level 10-20 dextrose solution |
| valproic acid | GI issues, Jaundice, hepatoxicity, thrombocytopenia, rash, drowsiness, headache |
| memantine | confusion, dizziness, constipation |
| donepezil | CNS effects, Nausea-vomiting Give HS |
| modafinil | headache, tachy, HTN |
| methylphenidate | insomnia, growth suppression in youth, heart dysrhythmia, HTN |
| amphetamine+dextroamphetamine sulfate | insomnia, nervousness,HTN, increased heart rate, palpations, weight loss, depression, tolerance, dependence |
| baclofen | cns depression, hypotension, fatigue, drowsiness, constipation, diarrhea Immediate withdrawl=kidney failure, severe spasms |