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Unit 3 Drugs

Central Nervous System

QuestionAnswer
First-generation NSAIDs - Inhibits COX-1,2 Aspirin (Acetylsalicylic Acid)
Nonaspirin first-generation NSAIDs- inhibits COX-1,2 Ibuprofen (Advil, Excedrin)
Second-Generation NSAIDs - (COX-2 inhibitors, coxibs) Celecoxib (Celebrex) <no effect on platelets>
Acetaminophen - (no anti-inflammatory agents) decreases fever and pain Tylenol <preferred for children,@ risk for hepatic necrosis> Non opioid analgesic
Acetylcysteine (Mucomyst) Decreases liver damage, protects within 10 hours of overdose. Treatment for Acute Toxicity of Acetaminophen.
Opioid analgesic Morphine sulfate (Morphine)
Strong Opioid Agonist Fentanyl (Duragesic) 100X stronger than morphine
Strong Opioid Agonist Transmucosal - Fentanyl losenges- (actiq) used for breakthrough pain in cancer pts.Transdermal- change q72 hrs
Synthetic Opioid Meperidine (Demerol) same effect as aspirinShort half-life, more toxic, causes restlessness, hallucinations, bizarre behavior.
Opioid Agonist, nonopioid analgesic (Vicodin; Lortab) Used in combo with Acetaminophen, Antitussive
Opioid Antagonist Naloxone (Narcan)- Reverses effects of OD of opioids.
Adjucant Analgesics Complement effects of opioids useful for neuropathic pain. Eg. Tricyclic Antidepressants, Anti seizure, lidocaine,Ritalin, local anesthetic
Antiepileptic drugs Phenytoin (Dilantin)<assess oral hygiene, high-risk for ginival hyperplasia.>
Antidepressant- SSRI's(Selective Serotonin Reuptake inhibitors) Fluoxetine (Prozac) Increases Seritonin by blocking the reuptake.
Antidepressant- SNRI's (Serotonin and NE reuptake inhibitors) Venlafaxine (Effexor)Increases Well-beingDecreases Anxiety
Benzodiazepine - sedative-hypnotic drugs Diazepam (Valium)Alprazolam (Xanax)Lorazepam (Ativan)Decreases anxiety, insomnia, seizure disorders.
Created by: abayly24279
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