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Tuberculosis 411
TB drugs
| Question | Answer |
|---|---|
| Causative organism for TB | Mycobacterium tuberculosis |
| Isoniazid ADRs | Peripheral neuropathy, liver dysfunction |
| Isoniazid pt info | take on empty stomach, don't discontinue, minimize alcohol, notify of signs of liver failure |
| Rifampin ADRs | Flu-like syndrome, hematopoietic (leukopenia, thrombocytopenia), hepatotoxicity |
| Rifampin pt info | empty stomach, don't discontinue, reddish-orange discoloration |
| Ethambutol ADRs | Optic neuritis |
| Ethambutol pt info | stomach upset, take w/ food, report loss of vision |
| Pyrazimamide (PZA) ADRs | gout, glucose intolerance, liver failure |
| Peripheral Neuropathy | Isoniazid |
| Liver Dysfunction | Isoniazid |
| Flu like syndrome | Rifampin |
| Hematopoietic SE's | Rifampim |
| Hepatotoxicity | Rifampin |
| Optic Neuritis | Ethambutol |
| Gout | PZA |
| Glucose intolerance | PZA |
| Liver Failure | PZA |
| Take on empty stomach, don't disc, min alcohol, notify MD of signs of liver failure | Isoniazid |
| Take on empty stomach, don't disc, reddish-orange color | Rifampin |
| May cause stomach upset, take w/ food, report loss of vision | Ethambotol |