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Antibiotics 411
Antibiotics
| Question | Answer |
|---|---|
| Systemic infection in which pathogens are present in the circulating bloodstream | Septicemia |
| Syndrome involving multiple system organ involvement that is a result of microorganisms or their toxins circulating in the blood | Sepsis |
| Invasion of body by pathogenic microorgs that reproduce and multiply, causing disease | Infection |
| Localized presence and multipication of microorgs w/out invasion or damage | Colonization |
| Presence of viable bacteria in the blood | Bacteremia |
| Staphylococcus category | Gram-positive cocci |
| Streptococcus category | Gram-positive cocci |
| Escherichia coli category | Enteric gram-negative Bacilli |
| Haemophilus influenza category | Gram-negative Bacilli |
| Pseudomonas category | Gram-negative Bacilli |
| Mycobacterium category | Acid-Fast Bacilli (AFB) |
| Aqueous penicillin G | Natural penicillin, gm+ anaerobes |
| Procain pen G | Natural penicillin, gm+ anaerobes |
| Benzathine pen G | Natural penicillin, gm+ anaerobes |
| Oxacillin | Penicillinase resistant, penicillinase producing gm+ orgs |
| Nafcillin | Penicillinase resistant, penicillinase producing gm+ orgs |
| Dicloxacillin | Penicillinase resistant, penicillinase producing gm+ orgs |
| Cloxacillin | Penicillinase resistant, penicillinase producing gm+ orgs |
| Ampicillin, Ampicillin/sulbactam | Aminopenicillin (Extended Spectrum), same gm+ as pen G, some gm- (E. coli, H. flu) |
| Amoxicillin, Amoxicillin/clavulanate | Aminopenicillin (Extended Spectrum) Same gm- as pen G, some gm- (E. coli, H. flu) |
| Carbenicillin | Antipseudomonal Penicillin, pseudomonas |
| Ticarcillin | Antipseudomonal Penicillin, pseudomonas |
| Piperacillin, Piperacillin/tazobactam | Antipseudomonal Penicillin, pseudomonas |
| Cephalexin | Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis |
| Cephradine | Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis |
| Cefadroxil | Cephalosporins-1st gen, gm+, little gm-, no H. flu, no B. fragilis |
| Cefaclor | Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu) |
| Cefuroxime axetil | Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu) |
| Cefprozil | Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu) |
| Loracarbef | Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu) |
| Cefixime | Cephalosporins-3rd gen, more gm-, less gm+, moderate against pseudomonas |
| Cefpodoxime | Cephalosporins-3rd gen, more gm-, less gm+, moderate against pseudomonas |
| Ciprofloxacin | Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella |
| Ofloxacin | Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella |
| Lomefloxacin | Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella |
| Trovafloxacin | Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella |
| Gatifloxacin | Fluoroquinolones, excellent gm- (H. flu), decent gm+, excellent shigella & salmonella |
| Erythromycin | Macrolides, gm+, gm- (H. flu), genital pathogens |
| Clarithromycin | Macrolides, gm+, gm- (H. flu), genital pathogens |
| Azithromycin | Macrolides, gm+, gm- (H. flu), genital pathogens |
| Tetracycline | Tetracyclines, gm+, gm-, acne |
| Metronidazole (Flagyl) | Misc, gm+ and gm- anaerobes |
| Clindamycin | Misc, gm+ and gm- aerobes and anaerobes (better than Flagyl against), protozoa |
| SMX-TMP | Misc, gm+ and gm- aerobes, chlamydia, protozoa, UTI & PCP infections |
| Imipenem/cilastin | Carbapenems, wide spectrum, powerful |
| Aztreonam | Monobactams, powerful gm-, high resistance |
| Vancomycin | Glycopeptides, powerful gm+, high resistance |
| Teicoplanin | Glycopeptides, powerful gm+, MRSA |
| Gentamicin | Aminoglycosides, powerful gm-, low resistance |
| Tobramycin | Aminoglycosides, powerful gm-, low resistance |
| Gentamicin & Tobramycin (Aminoglycosides) toxicity | otoxicity, nephrotoxicty |
| Natural Penicillins Spectrum | Gm+ anaerobes |
| Penicillinase resistant spectrum | penicillinase producing gm+ |
| Amonopenicillin (Extended Spectrum) spectrum | Same Gm+ as pen G, Gm- (salmonella, shigella, some E. coli, & H. flu) |
| Antipseudomonal Penicillin spectrum | Pseudomonas (gm-) |
| Cephalosporins-1st gen spectrum | gm+, little gm-, no H. flu, no B. fragillis |
| Cephalosporins-2nd gen spectrum | same gm+, addit gm- (H. flu) |
| Cephalosporins-3rd gen spectrum | gm-, less gm+, moderate against pesudomonas |
| Fluoroquinolones spectrum | excellent gm- (H. flu), decent gm+, shigella, salmonella |
| Macrolides spectrum | gm+, gm- (H. flu), genital pathogens, others: MAC, legionella, mycoplasma pneumonia, helicobacter pylori |
| Tetracyclines spectrum | decent gm+ and gm-, acne |
| Metronidazole spectrum | gm+ and gm- anaerobes |
| Clindamycin spectrum | gm+ and gm- anaerobes (better) and aerobes, protozoa |
| SMX-TMP spectrum | gm+ and gm- aerobes, chlamydia, protozoa, *UTIs, PCP* |
| Carbapenems/Imipenem/cilastin spectrum | wide, powerful, high resistance |
| Monobactams/Aztreonam spectrum | powerful gm-, high resistance |
| Glycopeptides/Vancomycin & Teicoplanin spectrum | powerful gm+, MRSA |
| Aminoglycosides/Gentamicin & Tobramycin spectrum | powerful gm-, low resistance |
| Oxacillin, Nafcillin, Dicloxacillin, Cloxacillin | Penicillinase resistant, penicillinase producing gm+ orgs |
| Ampicillin, Amoxicillin | Aminopenicillin, gm+ and gm- (more gm-) |
| Carbenicillin, Ticarcillin, Piperacillin | Antipseudomonal Penicillins |
| Cephalexin, Cephradine, Cefradoxil | 1st gen Cephalosporins, gm+. little gm-, no H. flu, no B. fragilis |
| Cefaclor, Cefuroxime axetil, Cefprozil, Loracarbef | Cephalosporins-2nd gen, same gm+ as 1st gen, addit gm- (H. flu) |
| Cefixime, Cefpodoxime | Cephalosporins-3rd gen, gm-, less gm+ |
| Imipenem/cilastin | Carbapenem |
| Axtrepnam | Monobactam, gm- |
| Vancomycin, Teicoplanin | Glycopeptides, gm+, MRSA |
| Gentamicin, Tobramycin | Aminoglycosides, gm- |