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Blood 411
Blood drugs
| Question | Answer |
|---|---|
| Heparin Onset of Action | Immediate |
| Anticoagulant DOC for pregnant women | Heparin |
| LMWHs drugs | Ardeparin, Dalteparin, Enoxaparin |
| LMWHs Route, Tests, ADRs | Subcutaneous, no tests, less bleeding |
| Glycoprotein IIb/IIIa Inhibitors drugs | Abciximab, Eptifibatide, Tirofiban |
| Anticoagulants | Heparin, Warfarin |
| Antiplatelet agents | Glycoprotein IIb/IIIa Inhibitors, Thienopyridines |
| Thrombolytics drugs | Alteplase, Anistreplase, Reteplase, Streptokinase, Urokinase |
| Glycoprotein IIb/IIIa Inhibitors MOA | Inhibit platelet aggregation by preventing binding of adhesion ligands to GP IIb/IIIa receptor on platelet |
| Thienopyridines drugs | Clopidogrel, Ticlopidine |
| Thienopyridines MOA | Inhibits platelet aggregation by binding to platelet ADP receptor |
| Thrombolytics Contraindications | Aneurysm, active bleeding, brain tumor, stroke, CNS surgery last 2 mos, severe HTN, trauma |
| Eptifibatide | Glycoprotein IIb/IIIa Inhibitors drugs |
| Tirofiban | Glycoprotein IIb/IIIa Inhibitors drugs |
| Ticlopidine | Thienopyridines drugs |
| Clopidogrel | Thienopyridines drugs |
| Abciximab | Glycoprotein IIb/IIIa Inhibitors drugs |
| Ardeparin | LMWHs drugs |
| Enoxaparin | LMWHs drugs |
| Dalteparin | LMWHs drugs |
| Alteplase | Thrombolytics drugs |
| Anistreplase | Thrombolytics drugs |
| Reteplase | Thrombolytics drugs |
| Streptokinase | Thrombolytics drugs |
| Urokinase | Thrombolytics drugs |
| Leukopenia | decreased WBCs |
| Leukocytosis | increased WBCs |
| Thrombocytopenia | decreased platelet conc. |
| Thrombocytosis | increased platelet conc. |
| Primary protein component. For osmotic pressure gradient | Albumin |
| Blood proteins that help protect body against infections | Globulins |
| Blood proteins that help with coagulation | Fibrinogen |
| Warfarin onset | Slow |
| Heparin Route | IV |
| Warfarin Route | PO |
| Heparin Duration | Short |
| Warfarin Duration | Long |
| Heparin Tests | aPTT |
| Warfarin Tests | PT, INR |
| Heparin Antidote | Protamine SO4 |
| Warfarin Antidote | Vitamin K |