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Blood 411

Blood drugs

Heparin Onset of Action Immediate
Anticoagulant DOC for pregnant women Heparin
LMWHs drugs Ardeparin, Dalteparin, Enoxaparin
LMWHs Route, Tests, ADRs Subcutaneous, no tests, less bleeding
Glycoprotein IIb/IIIa Inhibitors drugs Abciximab, Eptifibatide, Tirofiban
Anticoagulants Heparin, Warfarin
Antiplatelet agents Glycoprotein IIb/IIIa Inhibitors, Thienopyridines
Thrombolytics drugs Alteplase, Anistreplase, Reteplase, Streptokinase, Urokinase
Glycoprotein IIb/IIIa Inhibitors MOA Inhibit platelet aggregation by preventing binding of adhesion ligands to GP IIb/IIIa receptor on platelet
Thienopyridines drugs Clopidogrel, Ticlopidine
Thienopyridines MOA Inhibits platelet aggregation by binding to platelet ADP receptor
Thrombolytics Contraindications Aneurysm, active bleeding, brain tumor, stroke, CNS surgery last 2 mos, severe HTN, trauma
Eptifibatide Glycoprotein IIb/IIIa Inhibitors drugs
Tirofiban Glycoprotein IIb/IIIa Inhibitors drugs
Ticlopidine Thienopyridines drugs
Clopidogrel Thienopyridines drugs
Abciximab Glycoprotein IIb/IIIa Inhibitors drugs
Ardeparin LMWHs drugs
Enoxaparin LMWHs drugs
Dalteparin LMWHs drugs
Alteplase Thrombolytics drugs
Anistreplase Thrombolytics drugs
Reteplase Thrombolytics drugs
Streptokinase Thrombolytics drugs
Urokinase Thrombolytics drugs
Leukopenia decreased WBCs
Leukocytosis increased WBCs
Thrombocytopenia decreased platelet conc.
Thrombocytosis increased platelet conc.
Primary protein component. For osmotic pressure gradient Albumin
Blood proteins that help protect body against infections Globulins
Blood proteins that help with coagulation Fibrinogen
Warfarin onset Slow
Heparin Route IV
Warfarin Route PO
Heparin Duration Short
Warfarin Duration Long
Heparin Tests aPTT
Warfarin Tests PT, INR
Heparin Antidote Protamine SO4
Warfarin Antidote Vitamin K
Created by: lbreimeir



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