Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Pharm SFUPA derm
Pharm III SFU PA prog `2006 Prof KrekelDerm
| skin | skin 2 |
|---|---|
| Rule of 9's: each leg and foot % | 18% |
| Rule of 9's: each Arm and Hand % | 9% |
| Rule of 9's: each knee to toe% | 9% |
| Rule of 9's:Posterior Trunk% | 18% |
| Rule of 9's: Anterior Trunk% | 18% |
| Rule of 9's: head and neck | 9% |
| For TID application __ grams of cream cover __ % of skin daily | 9 grams 9% daily TID |
| Topical agents : Tretinoin, Podophyllum, Lindane who needs to be careful? why? | Pregnant and lactating women because harmful to fetus |
| what group is more prone to skin infections with steroid cream use? | old folks ( they have thinner skinthat absorbs more too) |
| Topical Agents : how much does a child absorb compared to an adult? | Kids absorb 3 times more then adults |
| Who absorbs the least amount of topical agents? | Young adults |
| Pt uses a topical agent ,skin gets worse what 3 things do they do? | Wash off ,stop using see provider |
| Topical Med (except acne) when should you see improvement? | 3-5 days if no improvment call provider |
| Can potent corticosteroids be used for diaper rash? | NO!!!!! |
| PT Ed. :topical agent how much ? how often? | "small amount, 2-4 x daily |
| Name 3 pody parts that hightly absorb topical meds | Scrotum,vulva and anus |
| if skin is burned, inflammed or traumatized : Effect on absorbtion? | Vastly increase amount absorbed |
| Absorbtion of scalp , face,arms and chest:: High Mod or low? | Moderate absorption |
| Name 2 area with low absorption of topical meds | Palm and Soles |
| Ointments: are | semi soild prep for external use |
| Ointments 3 functions; | 1Emollient, 2barrier, Vehicle: 3 incorporate meds |
| Most derm drug products are this type | creams |
| What is base of cream? | oil 50% water 50% |
| Cream the 50% water as apposed to the 20% inointment allow meds to penetrate what? be specific! | the stratum corneum ( the horny outer layer of the skin) |
| white petrolatum is an example of what? | Hydrocarbon based ointmnet |
| lanhydrous lanolin is an example of what? | ointment with an absoprtion base |
| hydrophilic petrolatum is an example of | ointment with an absoprtion base |
| can creams be used on hairy area? | yes ( pg 2 ) |
| what is a semisolid colloidal solution or suspension? contains alchohol? | Gel |
| If you need drying of the skin what can you use? | Gel |
| what provides better absorption? well hydrated or dry skin? | well hydrated ,soft supple skin absorbs better |
| for your ear canal , what skin med vehical? | solution |
| Hairy parts of the body : what vehicals can be considered? | solution ,lotion and creams surprisingly |
| what vehical to treat oozing and wet lesions? why? | Lotions: made of lots of water,which evaporates causing vasoconstricion ( less ooze) and reduced inflammation( less ouch) |
| Insoluable powders in a thick semi-occlusive ointment is classified as what type of vehical? | Paste |
| drug is dissolved entirely in the vehicle, whats it classified? | Solution |
| what should never be applied to skin folds or creases when the skin is weeping? | Powders |
| OK lotions are good for oozing and wet lesion, but what about wanting to dry sweaty oozing lesions? | Powder ( they decease friction too!) |
| Minimal Erythema Dose ..what? | amount of solar rad. to produce a min. skin redness |
| RATIO of the time required to produce minimal erythema with a sunscreen called? | SPF skin protection factor |
| who has a higher MED? Katie Curic or AL Roker? | Al Roker has a higher MED as he is much darker he can spend longer in the sun with out burning |
| this UV light IS NOT simply accerated aging BUT photoaging | UVA |
| UVA cause photoaging what is photoaging look like? | dry scaling, yellow,deeply wrinkled, thinner and mor fragile skin..Yikes! |
| UVA causes photoaging and what 2 other conditions? | Photo sensitivity drug reaction AND Basal Cell carcinoma are caused by whay UV light? |
| Psoriasis: name 9 pharmicological TXs | Emollients/Keratolyics, coal tar, anthralin, calcipotriene, corticsteriods(systemic and topical), sulfasalazine, methotrexate, retinoids |
| Tretinoin podophyllum and lindane what do they have in common? | Topical Drugs harmful to fetus |
| Cinnamates, Ethylhexylsalicylates, Benzopheones and PABA do what ? and used in what? | They all absorb a specific portion of the UV spectrum and are used in sunscreens usually 2or 3 of theese classes at a time. |
| Name 4 classes of drugs that are in sunscreens and act Chemically: | 1) PABA, 2) Cinnamates, 3) Ethylhexylsalicylates, 4) Benzopheones |
| Zinc Oxide, Red petrolatum and titanium dioxide are used in what and why? | The are used in Sun screens because they block and scatter harmfull rays they act PHYSICALLY |
| A adult in a swim suit , how much sun block per appplication? | 1 oz of sunblock is enough for who? how many times? |
| Very Water resistant sunscreen is good for how long frolicing in the water? | 80 mins in the water, what type of sunscreen? |
| What type of suinscreen if you are sweating (perspiring for 40 mins in the sun? | You need Water Resistant sunscreen if you are swimming or .......for how long? |
| SPF 30 blocks how much UVB? | 97% UVB is blocked by |
| SPF 15 blocks how much of what? | 93% UVB is blocked by |
| What doeASF 30+ offer over what | Slightly more UVB protection but more chance of a rash too |
| Skin Cancer foundation recommneds what SPF.. | SPF of at least 15is recommended by ... |
| Dermoplast spray whats it used for? | The most effect topical anesthetic for sunburn ( generic Benzocaine 20%) |
| Bezocaine 20% what is it used for? | The most effect topical anesthetic for sunburn ( Dermoplast) |
| Delayed erythema reaction form sunburn what can you take PO? | Ibuprofen is the best choise of Analgesic for what sunburn complication? |
| Medical help needed for a sunburned child with a __% burn | A 10 % burn ( or more )on a child indicates what ? |
| Dead skin is excellent for | A medium for microbial growth is |
| 25- Hydroxyvitamin D3 , who has low serm value? | Elderly or middle age folks that use daily sunscreen , what about their serum? |
| Zoloft, effexor, Elavil, TCA, Remeron have what in common? | Photosensitizers that are antidepressants |
| Zertec, benadryl, Claritin, Dramamine have what in comon? | Antihistamines that are photosensitizers |
| Zithromax, Quinalones( Cipro levaquine Avelox), Sulfoamides ( Bactrim), tetracyclines(Doxycycline, tetracycline, Minocycline) are what 2 things? | Antimicrobials that are photosensitizers |
| levaguin is a quinolnes that is the least... | Photosensitizer ( the least) that is a quinolones |
| Risperdal and Phenothiazines are what 2 things? | Antripsycotics that are photosensitizers |
| Amidioarone, ACE inhibitors, Diltiazem , Statins, Procardia are what 2 things? | Cardiovascular drugs that are photosensitizers |
| Diuretics that are photosensitizers | Thiazide diuretics :common, Loop diaretics some what less |
| Amaryl, Glucotrol, Diabeta, Micronase, and older sulfonylureas are what 2 things? | Hypoglycemic Sulfonylureas that are photosensitizers |
| Motrin , Naprosyn, feldene, Voltaren, Relafen, Lodine,Daypro what 2 things? | photosensitizers that are NSAIDS |
| Benzoyl peroxides, tegretol, Librium, O.C., Neurontin, Retin-A, Accutane and retnoids are all? | photosensitizers |
| What is the most common drug induced skin reaction? | maculopapular Eruptions |
| penicillin, Captopril, Cipro, Thiazide diuretics cause what skin reaction? | Maculopapular reactions |
| Asprin, Heprin, Ibuprofen, Naproxen, Opiates, Penicillins, Sulfonamides cause what drug skin reactions? | Urtucaris what drugs produce? |
| TX of uticaria | antihistamines ( when they fail Doxepin) |
| Macropapular reactions look like .. | Think measels as viral exanthems look like what drug /skin reaction? |
| TX maculopapular ? | fade within a few days, Pt Hx important |
| Erythematous or hyperpigmented round or oval lesions are a presentaion of what type of skin/ drug reaction? | Fixed drug reactions look like? |
| barbiturates, Metronidazole , phenothiazines , Sulfonamide, tetracycline are associated with what drug/skin reruption? | Fixed Drug Eruption |
| TX Fixed Drug Eruptions | Stop drug! Cool Water,bleach for hyper pigmnetation, corticosteroid and oral antihistamines of LITTLE VALUE |
| TX bee stings: | ICE |
| Kids 2-12 y/o repellant | DEET 10% but under 10 yo kids dont apply themselves |
| Kids > 12 yo, pregnant, adults DEET concentration | 50% DEET who? |
| Severe reactions to wasp stings what 3 Tx's? | benadrly OTC, Prednisone, Epi-Pen 0.3mg are 3 tx's for what ? |
| Epi-pens last .. | 18 months |
| for mild insect bites 5 TX's | ICE, hydrocotisone, antihistamines, anesthetics, counter -irritants |
| Urishiol is.. | oleoresin that oozes from Poison Ivory |
| Poison Ivory TX: prednisone | Oral Prednisone: 0.5 to 2mg/Kg/day tapered 14-21 days |
| Poison Ivory TX:: Sterapred DS-10mg | Sterapred DS-10mg start 60mg taper over 12 days |
| Poisen Ivory what hinders treatment? | Calamine ... good for Poisen ivy? |
| Topical TX Poison Ivy whats best? | Burows solution: Domeboto 1 tablet in 1 pint water wet dresing 15-30 min : 3-6x daily |
| Allergic Contact Dermatitis (ACD) what 2 phases? | sensitation phase and elicatation phase of what? |
| if ovr 25% of my body has poison Ivy what should I do? | get medical help! |
| psoriasis TX non pharm | light therapy UVB ( 290-340 nm) UVA ( 320-400nm) |
| What improves UVB Tx? | 1% Coal tar improves what psoriasis light thrapy/ |
| How long UVB TX for psoriasis? | 2-4 weeks |
| Mechinisim of UVA Tx? | Immunomodulatory MOA for what non pharm TX? |
| what improves UVA TX for psoriasis | psoralens plus UVA called PUVA |
| what forms are psoralens? | Methoxsalen (Uvadex) topical sol. and Methoxsalen (8-Mop) capsules, can also take a bath |
| freguency and lenght of TX for PUVA | 2-4 times week for 20-30 treatment |
| mild Moderate psoriasis and eczema can be treated | topically |
| List 9 types of pharm txs of psoriasis and Eczema | 1)Emollient/Keraatolytics, 2 ) Coal tar 3) Anthralin 4) Calciprtriene 5)corticosteroids systemic 6) corticosteriods Topical 7) Sulfasalazine 8) methotrexate 9) retinoids |
| MG217(15%) is | a coal tar shampoo |
| what psoriasis Tx if used on pustular or erythrodermic may cause extensive skin irritation ,leading to Koebners phenomenon? | Coal Tar |
| a pt you are Tx for psoriasis developes N?V tinnitis or hyperventilation what are you Txing them with? | Salyclic acid a keratolytic |
| 5% Coal tar Soln= | 1% Coal tar |
| MOA Keratolytics: | decress cohesion of corneocytes in abnormal horny layer ( does not effect normal skins) |
| MOA Coal tar | decrease cell mitosis scale development, reduce sebum and cross link with DNA |
| Antroderm or Drithro creme are: | Anthralins |
| MOA Anthralin | decrease mititic rate by inhibit DNA synthesis , upset oxadative metabolic process slowing epidermal mitosis |
| Calcipotriene MOA | inhipits sell proliferation decrease Tcell proliferation |
| Devonex ointment,cream or sol is | Calcipotriene |
| Causes purple brown stains on skin hair and fabric | Anthralin ( AntraDerm or Drithrocreme) |
| methotrexate starting dose | 7.5 mg /week ; 2.5 mg every 12 hrs for 3 doses every week |
| methotrexate max dose and why | 25mg /week because over 20mg /week cause bone marrow supresion |
| Soriatane ( acitretin) | cost $500.00 oral retinoid Retinoids |
| Tazorac ( tazarotene) | Cream and gel Retinoid that decreases cell proliferation and hyperplasia |
| positive responce to psorisia tx is what 3 things? | 1) normalization of skin 2) decreased erythema and scales 3) reduced elevation of plaques |
| TX seborrheic dermatitis | topical steroids up to 7 days, Nizoral A?D shampoo 2xweek leave on 3 min |
| Eyelids Tx seborrheic dermatitis | low potency corticosterios ( not sterile ) |
| TX seborrheic derm , Thorax | use lotion,solution (or foam) on hairy areas |
| Tx of head lice DOC | Nix creme rince 1% on hair NO longer then 10 minutes |
| TX scabies DOC | Elimite cream 5% |
| What is NIX and Elimite made of? | permethrin |
| Permethrin caution with | asthmatics |
| Permethrin not recommended for | nursing women |
| Lindane MOA | neurotoxic to head lice and their eggs and woops peopke too |
| Lindane lotion how and how long | neck down leave on 8-12 hours |
| Scabicidal and antiprurutic TX | Crotamition |
| Crotamition (Eurax)problem? clue: peeu! | 3days with out a shower |
| I am taking welbutrin, theophyline, quinolones,antidepressants, meperdine and methocardamol AND i have head lice what TX should I NOT use? | Lindane has cause seizures and death |
| Ok if its not safe for your lawn, flammale and an organophosphosphate cholinestrtase why would you use this? even if you have head lice what am I talking about? | Malathion |
| How often can you use Malathion? | reapply in 7-9 days only if required |
| Actinic Keratosis name 3 drugs | 1) vitamin-E cream, 2) 5-FU cream(carac cream, Efudex) 3) Imiquimod ( Aldara) |
| Imiquidmod(Aldara) is used to treat what 2 conditions? | HPV pg51 and Actinic Keratosis |
| Tx of Acne Rosacae | (topical and systemic antibiotics) if svere isotretinoin, and topical metronidazole |
| Antibiotics for Acne rosacae? | doxycycline,minocycline or tetracycline but if pregnant Erthromycin |
| silver sulfadiazine (silverdene) for TX of and waring | Burns and pregnant women and near term infants kernicterus, hypersensitivity to sulfer and silver |
| list 8 clases of Acne pharm TXs | 1)Benzoyl peroxide 2)Azelaic Acid, 3)Retinoids 4)Keratolytics 5)top.antibx 6) systemic Antibx 7)O.C. 8) Isotretinoin |
| Ortho-Tri-Cyclen what skin condition can it tx and why? | It is an OC that uses norgestimate ( wich is minimally androgenoc ) and is uded to Tx moderate Acne |
Created by:
pnelson
Popular Pharmacology sets