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Acute decomp HF

Stack #28571

QuestionAnswer
s/s of Left Ventricular HF Dyspnea on Exertion, Orthopnea, Pulmonary Edema, Rales
s/s of Right Ventricular HF Abdominal pain, Anorexia, Bloating, peripheral edema, ascites
Hemodynamic subset I No specific intervention
Hemodynamic subset II Dobutamine and/or loop or NTG
Hemodynamic subset III PAOP <15 First give IV fluids then if PAOP is between 15-18 dobutamine and /or nitroprusside
Hemodynamic subset III PAOP 15-18 nitroprusside or dobutamine or milirone and nitroprusside or NTG
Hemodynamic subset IV Nitroprusside or Dobutamine+ milrinone
Dopamine MOA Directly stimulates adrenergic receptors as well as release CCA's
Dopamine SE Arrhythmias, Angina. Long term use increase mortality
Dobutamine MOA Racemic mixture:+dobutamine, is a B1 and 2 agonist and partial alpha agonist
Dobutamine Administration infusion pump;2.5-20 mcg/kg/min titrate at 5mcg/kg/min
Dobutamine Benefits Less mycardial o2 demand and great post MI. WIll last 3-7 days
Dobutamine SE Tachycardia, arrhythmias, angina, long term use increase mortality
Milrinone MOA PDE inhibitor will increase intracellular cAMP and thus increase intracellular Ca, increase contraction
Milirinone Administration infusion pump; 5-10 mcg/kg/min
Milirinone Benefit Decrease SVR, increase CO, and decrease PCWP, onset in 10 minutes
Milirinone SE Hypotension, thrombocytopenia, increase HR, arrhythmias, fever, LFT increase.
Milirinone monitor Renal adjust, HR, MAP, SVR, BP, CO, Scr
Nitroprusside MOA Mixed arterial/venous dialator, produced NO
Nitroprusside Administration infusion pump, 0.25-3mcg/kg/min
Nitroprusside benefits Decrease SVR, PCWP, increase CO onset is in 10 minutes
Nitroprusside SE Hypotension, thiocyniate/cyanide toxcity
Nitroprusside Monitor BP, MAP, SVR (triple cath), LFT, renal function
Nitroglycerine MOA PRimary venousdialator, mild arterial dialator
Nitroglycerine Administration infusion pump, 5-200mcg/kg/min
Nitroglycerine benefit Decrease PCWP, SVR
Nitroglycerine SE Hypotension, Increase HR, nitrate tolerance
Nitroglycerine Monitor PCWP(Catheter) BP, MAP, Chest pain
Nesiritide MOA Human b peptide, increases Cyclic GMP
NesiritideAdministration 2mcg/kg bolus, then 0.01 mcg/kg/min continus infusion
Nesiritide benefit Decrease PVR, SVR, PCWP, aldosterone, EPI
Nesiritide SE Hypotension, and long t1/2 (3-4 hrs), reflex tachycardia
Nesiritide Monitor Urine out/input, Na, BP, MAP
Vasopressin MOA Dialate renal mesinteric arteries of kidney, and increase ANP
Vasopressin Asministration 0.01-0.04 U/min continous infusion
Vasopressin Benefits Improve renal profusion
Vasopressin SE Ischemia, metabolic acidosis, cramping, hyponatremia, sweating, tremor
Vasopressin Monitor Urine out/in put, BUN/Scr
Furosemide MOA Decrease Na/water reabsorption
Furosemide Administration 20-80 mg IV repeated every 4-6 times per day
Furosemide Benefit Decrease PCWP, intravascular volume, preload, and pulmonary congestion.
Furosemide SE Volume depletion, electrolyte imbalance, azeotemia( overdiuresis), otoxcity (3mg/min)
Furosemide Monitor Urine in/output, Clcr, Scr
Created by: liza001
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