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Pharmacology Exam 1

Questions, Definitions, Drugs, Side Effects

What is the study of the movement of drugs through the body? Pharmacokinetics
What are the four types of movement of drugs? Absorption, Distribution, Metabolism, and Excretion
What is the impact of drugs on the body and how they do it? Pharmacodynamics
What is the movement of drugs that involves the movement of a drug from the site of administration to the blood stream? Absorption
What is the drug movement from the blood to the interstitial spaces and from there to the cells? Distribution
What is the most important organ used for excretion? Kidneys
What is the movement of drugs and metabolites out of the body? Excretion
What are the molecules that activate receptors? Agonist
What produces their effects by preventing receptor activation by endogenous regulatory molecules and drugs? Antagonist
What organ is mostly responsibly for metabolism? Liver
What is the amount of drug that we must give to elicit a response? Potency
What is it called when a drug is extensively inactivated as it passes through the liver? First Pass Effect
Which protein is most abundant in the blood? Albumin
What are common assessments associated with Parkinson's disease? Tremors, slurred speech, trouble speaking, constipation, depression, and difficulty speaking, pill rolling, shuffling gait.
What medication is used to treat Parkinson's? Carbidopa/Levadopa
What medication is used to treat osteoporosis? Alendronate (Bisphosphonates), Vitamin D, and Calcium
Which types of food should you avoid when taking Carbidopa/Levadopa? Foods high in protein.
What is a medication used to depress the muscle spasms exhibited in Multiple Sclerosis? Baclofen
What are the common side effects of Baclofen? Dizziness, drowsiness, abdominal pain, nausea, urinary retention, and decreased respiratory rate.
If a patient needs to stop taking Baclofen, what is a safe way to do so? A patient should stop taking the medication slowly over the course of a week.
What will happen if you stop taking Baclofen immediately? A patient may have rebound muscle spasms and seizures.
What precautions should you give the patient when they begin taking Baclofen? Don’t mix with alcohol or other CNS depressants (sleep, pain, etc) and avoid preforming hazardous tasks until you know how the medication will effect you.
What is an emergency medication used to treat Myasthenia Graves? Edrophonium
What medication is given on a daily basis in order to control Myasthenia Graves? Pyridostigmine
What common fruit juice interacts with many medications? Grapefruit juice
What is the quickest route of administration? Intravenous
What is the therapeutic range? The distance between minimum effective concentration and minimum toxic concentration.
What is it important for a nurse to do when she is aware that a drug has a narrow therapeutic range? Frequently monitor the patient for toxic effects.
What is a food drug interactions associated with Caribopa/Levadopa? Protein will inhibit the absorption of the medication decreasing its therapeutic effects.
Created by: KimeleS