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Bivalirudin (paren)
ANTICOAGULANTS (Direct thrombin inhibitors)
| Term | Definition |
|---|---|
| Indication | ACS (Acute coronary syndrome) |
| Contraindication | Risk of bleeding |
| Adverse effects | Severe bleeding (common) Thrombocytopenia Nausea |
| Mode of action | For direct thrombin inhibitors: inhibit both free and fibrin-bound thrombin, preventing fibrinogen converting to fibrin, prevent thrombus formation |
| Dose/Route | IV bolus then infusion |
| Comment | use with aspirin |
| How to remember | Bi và li rủ đi |