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Bivalirudin (paren)
ANTICOAGULANTS (Direct thrombin inhibitors)
Term | Definition |
---|---|
Indication | ACS (Acute coronary syndrome) |
Contraindication | Risk of bleeding |
Adverse effects | Severe bleeding (common) Thrombocytopenia Nausea |
Mode of action | For direct thrombin inhibitors: inhibit both free and fibrin-bound thrombin, preventing fibrinogen converting to fibrin, prevent thrombus formation |
Dose/Route | IV bolus then infusion |
Comment | use with aspirin |
How to remember | Bi và li rủ đi |