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Cardiovascular Drugs
| Drugs | Category | Action | Use | Notes |
|---|---|---|---|---|
| Propranolol | sympatholytic | non selective beta blocker | Hypertension Anti arrhythmic - Class Ii | |
| Prazosin | sympatholytic | alpha-1 blocker | Hypertension | |
| Sodium nitroprusside | vasodilator | NO donor | Hypertension Edema | Short acting, IV for emergencies smooth muscle relaxation Need to counter compensatory BaroRc/renin-angiotensin response |
| Verapramil | vasodilator | Ca2+ channel blocker | Hypertension Edema Anti arrhythmic - Class IV | smooth muscle relaxation Need to counter compensatory BaroRc/renin-angiotensin response |
| Enalapril | ACE inhibitor | Hypertension Mild heart failure | Side effects cough | |
| Losartan | AT1 Rc Blocker | |||
| Hydrochlorothiazide | Thiazide diuretic | Inhibit ion reabsorption and DCT | Hypertension - lower blood volume Edema Mild heart failure | |
| Furosemide | Loop diuretic | Inhibit ion reabsorption at Loop | Hypertension - lower blood volume Edema Mild heart failure | Rapid, short acting |
| Nitroglycerin | vasodilator (nitrate) | no --> increase cGMP --> relax smooth muscle --> vasodilation | Angina | |
| Digoxin | Cardiac Glycoside | Inhibits Na/K ATPase | Following treatment with sympatholytic Direct (hart - increase Na in cells)) and indirect (BaroRc - lower SNS activity) effects | Quinidine lowers clearance |
| Quinidine | Anti arrhythmic - Class IA Na channel blocker | Blocks active Na channel | ||
| Lidocaine | Anti arrhythmic - Class IB Na channel blocker | Blocks Na channel | Ventricular fibrillation/tachycardia | Emergency ONLY |
| Amiodarone | Anti arrhythmic - Class III | Blocks K channel - prolongs AP | ||
| Clonidine | sympatholytic | Centrally acting - alpha-2 agonist | Hypertension | Side effects - sedation, impaired concentration |
| Metoprolol | sympatholytic | Beta-1 blocker | Hypertension Tachycardia Anti arrhythmic - Class Ii | lowers renin release in kidney, CO |