Save
Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't know
Remaining cards (0)
Know
0:00
share
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Anti-VFPHI

Antivirals, Antifungals, Antiparisitics, Antihistimines, Antiinflammatory

DrugClass/Family
acyclovir -cyclovir / Antiviral / Inhibition of viral DNA synthesis / Herpes Simplex V, Varicella Zoster V, cytomegalovirus, Epstein-Barr virus / Renal Clearance / Nephrotoxicity, neurotoxicity / Interaction with zidovudine
ganciclovir -cyclovir / Antiviral / Inhibition of viral DNA synthesis / Herpes Simplex V, Varicella Zoster V, cytomegalovirus, Epstein-Barr virus / Renal Clearance / Nephrotoxicity, neurotoxicity / Interaction with zidovudine
foscarnet no root / Antiviral / Inhibition of viral DNA polymerase, RNA polymerase & HIV reverse transcriptase / HSV, VZV, cytomegalovirus, Epstein-Barr virus / NOT FIRST LINE / Renal Elimination / Nephrotoxicity /
amantadine -mantadine / Antiviral / Inhibition of viral uncoating / Influenza A/ NOT Commonly Used / Very common resistance / <5% have CNS toxicity / Interaction with antihistamines, anticholinergics, alcohol
oseltamivir -amivir / Antiviral / Neuraminidase Inhibitor / Inhibition of viral budding / Influenza A & B / MUST BE USED IMMEDIATELY / Resistance fairly common / CI distress, Pregnancy Category C / Interaction with live vaccines
zanamivir -amivir / Antiviral / Neuraminidase Inhibitor / Inhibition of viral budding / Influenza A & B / MUST BE USED IMMEDIATELY / Resistance fairly common / CI distress, Pregnancy Category C / Interaction with live vaccines
ribavirin no root / Antiviral / inhibition of IMPDH leads to depletion of GTP levels, can also inhibit viral RNA polymerase / Hepatitis C / Interacts with zidovudine / Pregnancy category X / Anemia
zidovudine no root / Antiviral / Nucleoside Reverse Transcriptase Inhivitor (NRTI) (Thymidine homolog) / HIV / RARELY USED NOW because of frequent drug interactions / Granulocytopenia, metabolic lactic acidosis
nevirapine no root / Antiviral / Non-nucleoside Reverse Transcriptase Inhibitor / HIV / CYP P450s Clearance / rash, liver toxicity
indinavir no root / Antiviral / HIV-protease inhibitor / HIV / RARELY USED NOW / CYP P450s Clearance / Altered lipid metabolism & fat redistribution, nephrolithiasis
caspofungin -fungin / Antifungal / Cell wall synthesis by inhibiting 1,3-beta glucan synthase. Fungicidal / Invasive candidiasis, aspergillosis / Very well-tolerated / Hepatic clearance / IV infusion / Interaction with immunosuppressants
amphotericin B no root / Antifungal / Binds ergosterol in fungal membranes and forms a pore / Broad-spectrum for severe fungal infections / IV infusion / Renal clearance / Side effects are "amphoterrible"
terbinafine no root / Antifungal / inhibits ergosterol synthesis enzyme squalene epoxidase decreases mebmrane fluidity and integrity / dermatophytes
fluconazole -conazole / Antifungal / interfere with ergosterol synthesis inhibit lanosteral-14 alpha demethylase / superficial and systemic fungal infections / CSF distribution / Renal elimination
itraconazole -conazole / Antifungal / interfere with ergosterol synthesis inhibit lanosteral-14 alpha demethylase / superficial and systemic fungal infections / hepatotoxicity / NOT CSF / Metabolic clearance
flucytosine no root / Antifungal / inhibits DNA synthesis, converted to 5'fluorouracil (toxic) / systemic fungal infections (used with amphotericin B to treat cryptococcal meningitis / renal eliminated / CONTRAINDICATED during pregnancy
griseofulvin no root / Antifungal / binds microtubules, mitosis inhibitor / restricted to dermatophytes / must be used until injured tissue replaces itself
pentamidine no root / Antifungal / poorly understood mechanism, interacts with DNA, RNA, topoisomerase, and ubiquitin / Alternative treatment for pneumocystitis jiroveci pneumonia / nephrotoxiticy, cardiovascular, hypoglycemia / NO CNS penetration
trimethroprim (TMP) / sulfamethoxazole (SMX) no root / Antifungal & Antibacterial / folate antagonist / SMX inhibits dihydropteroate synthase (DHPS) / TMP inhibits dihydrofolate reductase (DHFR) /
metronidazole Antiparisitic / lots
chloroquine Antiparisitic / malaria
quinine/quinidine Antiparisitic / malaria
gluconate Antiparisitic / cutaneous or visceral leishmaniasis
atovaquone-proguanil Antiparisitic / Babesiosis
primaquine Antiparisitic / malaria
sulfadiazine/pyrimethamine Antiparisitic / malaria
sodium stibogluconate Antiparisitic / Visceral leishmaniasis
nifurtimox Antiparisitic / American trypanosomes/Chagas’ disease
suramin Antiparisitic / African sleeping sickness
melarsoprol Antiparisitic / African sleeping sickness
mebendazole Antiparisitic / whipworm
pyrantel pamoate Antiparisitic / hookworms
ivermectin Antiparisitic / threadworm
praziquantel Antiparisitic / Flatworms and cestodes
diphenhydramine Antihistamine / 1st Gen H1 receptor antagonist (sedation) / Widely distributed in body including CNS / Competitive Inhibitor / Used in allergic reactions, cold and flu, motion sickness, parkinson's
promethazine Antihistamine / 1st Gen H1 receptor antagonist (sedation) / Widely distributed in body including CNS / Competitive Inhibitor / Used in allergic reactions, cold and flu, motion sickness, parkinson's
dimenhydrinate Antihistamine / 1st Gen H1 receptor antagonist (sedation) / Widely distributed in body including CNS / Competitive Inhibitor / Used in allergic reactions, cold and flu, motion sickness, parkinson's
chlorpheniramine Antihistamine / 1st Gen H1 receptor antagonist (sedation) / Widely distributed in body including CNS / Competitive Inhibitor / Used in allergic reactions, cold and flu, motion sickness, parkinson's
cetirizine Antihistamine 2nd Gen H1 Receptor Antagonist / NOT distributed to CNS, more selective for peripheral H1 receptors / Inhibits H1 receptor / Used for allergic reactions
loratadine Antihistamine 2nd Gen H1 Receptor Antagonist / NOT distributed to CNS, more selective for peripheral H1 receptors / Inhibits H1 receptor / Used for allergic reactions
fexofenadine Antihistamine 3rd Gen H1 Receptor Antagonist / Increased efficacy & fewer adverse effects / Inhibits H1 receptor / Used for allergic reactions
acetylsalicylic acid Anti-inflammatory (NSAIDs) / Aspirin / Low doses have an anti-thrombotic effect / Intermediate doses as an analgesis, antipyretic, anti-inflammatory effects by inhibition of COX-1 & 2/ High doses as anti-inflammatory effects in rheumatic disorders
celecoxib Anti-inflammatory (NSAIDs) / Selective inhibition of COX-2 with minimal effect on COX-1 / GI side effects and Renal toxicity less than other NSAIDs. / No significant inhibition of platelet aggregation / Potential for MI or stroke / Pain, swell, infla
ibuprofen Anti-inflammatory (NSAIDs) / non-selective, reversible inhibition of COX-1 and COX-2 / lowest incidence of GI side ffects of all NSAIDs / Fever, mild to moderate pain, inflammation
naproxen Anti-inflammatory (NSAIDs) / non-selective, reversible inhibition of COX-1 and COX-2 / smallest overall cardiovascular risks of NSAIDs / Fever, mild to moderate pain, inflammation
Created by: carchase
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards