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Antagonist/Antidose
Advanced Pharm
Question | Answer |
---|---|
acetylcysteine (Mucomyst) | antidote for acetaminophen hepatotoxicity |
unlabeled use for acetylcysteine (Mucomyst) | given before nephrotoxic exposure occurs to prevent kidney damage |
standard max daily dose of acetaminophen | 3,000 mg |
activated charcoal (Actidose) | preferred method of poisoning and OD of ASA, APAP, antidepressants, barbiturates, and others |
aminocaproic acid (Amicar) | antifibrinolytic; treats excessive bleeding from surgery or overactivation of fibrinolytic system |
deferoxamine mesylate (Desferal) | chelating agent; adjunctive treatment of acute Fe intoxication |
digoxin immune FAB (Digibind) | life-threatening OD of digoxin |
disulfiram (Antabuse) | adjunct in management of chronic alcoholism |
flumazenil (Romazicon) | benzodiazepine antagonist |
ipecac syrup | induction of vomiting in poisoning |
naloxone hydrochloride (Narcan) | reversal of narcotic induced respiratory depression, coma, analgesia |
succimer (Chemet) | chelating agent for Pb poisoning in children w/ blood levels >45 mcg/dl |
glucagon | hypoglycemia |
phentolamine (Regitine) | tx and prevention of dermal necrosis and sloughing after IV extravasation of catecholamines; control BP with pheochromocytoma |
physostigmine salicylate (Antilirium) | cholinergic drug; tx of poisoning by atropine and other anticholinergic drugs |
phytonadione (Vitamin K) | antihemorrhagic; hyperprothrombinemia |
protamine sulfate | heparin antagonist |
sodium polystyrene sulfonate (Kayexalate) | K-removing resin tx of hyperkalemia |