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Antagonist/Antidose

Advanced Pharm

QuestionAnswer
acetylcysteine (Mucomyst) antidote for acetaminophen hepatotoxicity
unlabeled use for acetylcysteine (Mucomyst) given before nephrotoxic exposure occurs to prevent kidney damage
standard max daily dose of acetaminophen 3,000 mg
activated charcoal (Actidose) preferred method of poisoning and OD of ASA, APAP, antidepressants, barbiturates, and others
aminocaproic acid (Amicar) antifibrinolytic; treats excessive bleeding from surgery or overactivation of fibrinolytic system
deferoxamine mesylate (Desferal) chelating agent; adjunctive treatment of acute Fe intoxication
digoxin immune FAB (Digibind) life-threatening OD of digoxin
disulfiram (Antabuse) adjunct in management of chronic alcoholism
flumazenil (Romazicon) benzodiazepine antagonist
ipecac syrup induction of vomiting in poisoning
naloxone hydrochloride (Narcan) reversal of narcotic induced respiratory depression, coma, analgesia
succimer (Chemet) chelating agent for Pb poisoning in children w/ blood levels >45 mcg/dl
glucagon hypoglycemia
phentolamine (Regitine) tx and prevention of dermal necrosis and sloughing after IV extravasation of catecholamines; control BP with pheochromocytoma
physostigmine salicylate (Antilirium) cholinergic drug; tx of poisoning by atropine and other anticholinergic drugs
phytonadione (Vitamin K) antihemorrhagic; hyperprothrombinemia
protamine sulfate heparin antagonist
sodium polystyrene sulfonate (Kayexalate) K-removing resin tx of hyperkalemia
Created by: spham