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Receptors-Tissues
Phipp's list of which receptors effect which tissues.
| Organ System/Fxn | Receptor |
|---|---|
| Iris contraction (radial/mydriasis) | Alpha-1 |
| Iris contraction (sphincter/miosis) | M3,M2 |
| Ciliary (relax for far vision) | Beta-2 |
| Ciliary (contract for near vision) | M3,M2 |
| Lacrimal secretion+ | Alpha |
| Lacrimal secretion+++ | M3,M2 |
| SA node (HR increase) | Beta-1 > Beta-2 |
| SA node (HR decrease) | M2 > > M3 |
| Atria (Inc contract&conduction)++ | Beta-1 > Beta-2 |
| Atria (decrease in contract& shortened AP dur) | M2 > > M3 |
| AV node (Inc in automaticity&conduction) | Beta-1 > Beta-2 |
| AV node (decrease in conduction+AV block) | M2 > > M3 |
| His-Purkinje system (inc. in automaciticy&conduction) | Beta-1>Beta-2 |
| His-Purkinje sys (little/no parasym effect) | M2 > > M3 |
| Ventricle (Inc. contract/conduct/pacemakers/automaticity) | Beta-1 > Beta-2 |
| Ventricle (slight decrease in contract) | M2 > > M3 |
| Coronary (Constrict+;dilation++) | Alpha-1, Alpha-2; Beta-2 (No parasymp) |
| Skin/mucosa (Constrict++) | Alpha-1, Alpha-2 (no parasymp) |
| Skeletal Muscle (Constrict;dilation++) | Alpha-1; Beta-2 |
| Skeletal Muscle (Dilation) | ? |
| Cerebral (constriction, slight) | Alpha-1 (no parasymp) |
| Pulmonary (constriction+;dilation) | Alpha-1; Beta-2 (no parasymp) |
| Abdom. Viscera (constrict+++;dilation++) | Alpha-1; Beta-2 (no parasymp) |
| Salivary glands (Constriction+++) | Alpha-1,Alpha-2 |
| Salivary Glands (dilation++) | M3 |
| Renal (constriction++; dilation++) | Alpha-1,Alpha-2; Beta-1, Beta-2 (no parasymp) |
| Veins (constriction;dilation) | Alpha-1,Alpha-2; Beta-2 |
| Endothelium (Activation of NO synthase | M3 |
| Tracheal/Bronchial smooth muscle. (Relaxation) | Beta-2 |
| Teacheal/Bronchial smooth muscle (Contraction) | M2=M3 |
| Bronchial Glands (lower secretion) | Alpha-1 |
| Bronchial Glands (increase secretion) | Beta-2 |
| Bronchial Glands (Stimulation) | M3,M2 |
| Stomach Motility/Tone (decrease) | A1,A2,B1,B2 |
| Stomach Motility/Tone (Increase) | M2=M3 |
| Stomach Sphincters (contract) | A1 |
| Stomach Sphincters (relax) | M3,M2 |
| Stomach Secretion (inhibit) | A2 |
| Stomach Secretion (stimulate) | Food. (M3,M2) |
| Intestine Motility/Tone (decrease) | A1,A2,B1,B2 |
| Intestine Motility/Tone (increase) | M3,M2 |
| Intestine Sphincters (contract) | A1 |
| Intestine Sphincters (relax) | M3,M2 |
| Intestine Secretion (inhibit) | A2 |
| Intestine Secretion (stimulate) | M3,M2 |
| Gallbladder/Ducts (Relax) | B2 |
| Gallbladder/Ducts (contract) | M |
| Kidney Renin Secretion (decrease;increase) | A1 ; B1 (no parasymp) |
| Bladder Detrusor (relax) | B2 |
| Bladder Detrusor (contract) | M3 > M2 |
| Bladder Trigone/Sphincter (contract) | A1 |
| Bladder Trigone/Sphincter (relax) | M3 > M2 |
| Ureter Motility/Tone (Increase) | A1 & (M? typo in list?) |
| Uterus Pregnancy (Contraction;Relax) | A1;B2 maybe M also? |
| Uterus Non-pregnant (Relax) | B2 |
| Sex Organs:Male (Ejaculation) | A1 |
| Sex Organs:Male (Erection) | M3 |
| Skin:Pilomotor muscles (Contract) | A1 |
| Sweat Glands (local secretion) | A1 |
| Sweat glands (general secretion) | M3,M2 |
| Spleen Capsule (Contraction) | A1 |
| Spleen Capsule (relax) | B2 |
| Adrenal medulla (Secretion of Epi&NE) | N(A3 secondarily, B4 third); M |
| Skel Muscle (Increased contractility; flycogenolysis; K+uptake) | B2 |
| Liver (Glycogenolysis & Gluconeogenesis) | A1,B2 |
| Pancreas Acini (decrease secretion) | A |
| Pancreas Acini (increase secretion) | M3,M2 |
| Pancreas Islets (decrease secretion) | A2 |
| Pancreas Islets (increase secretion) | B2 |
| Fat cells (lipolysis/thermogenesis) | A1,B1,B2,B3 |
| Fat cells (inhibit lypolysis) | A2 |
| Salivary glands (K+ / H2O secretion)+ | A1 |
| Salivary glands (K+ / H2O secretion)+++ | M3,M2 |
| Nasopharyngeal glands (secretion) | M3,M2 |
| Pineal glands (melanton synth) | B |
| Posterior Pituitary (ADH secretion) | B1 |
| Autonomic Nerve Endings (Symp terminals Autoreceptor inhibition of NE release) | A2a > A2c(A2b) ? |
| Autonomic Nerve Endings (Symp terminals heteroreceptor inhibition of NE release) | M2,M4 |
| Autonomic Nerve Endings (parasymp terminal autoreceptor inhibition of ACh release) | M2, M4 |
| Autonomic Nerve Endings (parasymp terminal heteroreceptor inhibition of ACh release) | A1a > A2c |
Created by:
SU2012
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