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Diabetes Mellitus
Pharmacology Mod B - Diabetes Mellitus
| Term | Definition |
|---|---|
| RAPID-ACTING INSULIN | -NovoLog (aspart) -Humalog (lispro) -Apidra (glulisine) |
| SHORT-ACTING INSULIN | -Humulin R (human) -Novolin R (human) |
| INTERMEDIATE-ACTING INSULIN | -Humulin N (human) -Novolin N (human) |
| LONG-ACTING INSULIN | -Lantus (glargine) -Toujeo (glargine) -Levemir (detemir) |
| NovoLog (aspart) ONSET - rapid | 0.2 - 0.33 |
| Humalog (lispro) ONSET - rapid | 0.2 - 0.33 |
| Apidra (glulisine) ONSET - rapid | 0.2 - 0.33 |
| NovoLog (aspart) PEAK - rapid | 1 - 3 |
| Humalog (lispro) PEAK - rapid | 0.5 - 2.5 |
| Apidra (glulisine) PEAK - rapid | 0.5 - 1.5 |
| NovoLog (aspart) DURATION - rapid | 3 - 5 |
| Humalog (lispro) DURATION - rapid | 3 - 6.5 |
| Apidra (glulisine) DURATION - rapid | 4 - 5 |
| Humulin R (human) ONSET - short | 0.5 - 1 |
| Novolin R (human) ONSET - short | 0.5 - 1 |
| Humulin R (human) PEAK - short | 2.5 - 5 |
| Novolin R (human) PEAK - short | 2.5 - 5 |
| Humulin R (human) DURATION - short | 5 - 10 |
| Novolin R (human) DURATION - short | 8 |
| Humulin N (human) ONSET - intermediate | 1 - 2 |
| Novolin N (human) ONSET - intermediate | 1 - 2 |
| Humulin N (human) PEAK - intermediate | 4 - 12 |
| Novolin N (human) PEAK - intermediate | 4 - 12 |
| Humulin N (human) DURATION - intermediate | 16 - 28 |
| Novolin N (human) DURATION - intermediate | 24 |
| Lantus (glargine) ONSET - long | 1.1 |
| Toujeo (glargine) ONSET - long | 1.1 |
| Levemir (detemir) ONSET - long | 1 |
| Lantus (glargine) PEAK - long | n/a |
| Toujeo (glargine) PEAK - long | n/a |
| Levemir (detemir) PEAK - long | n/a |
| Lantus (glargine) DURATION - long | 24 |
| Toujeo (glargine) DURATION - long | 24 |
| Levemir (detemir) DURATION - long | up to 24 |
| HYPOGLYCEMIA | -abnormal low blood glucose level -below 70 mg/dL -"COLD & CLAMMY = NEED SOME CANDY" |
| HYPERGLYCEMIA | -excess of glucose in the bloodstream -above 100 mg/dL -"HOT & DRY = SUGAR HIGH" |
| TYPE 1 DM | -caused by autoimmune destruction of the beta cells -beta needs insulin -insulin therapy -diabetic ketoacidosis and hyperosmolar non-ketonic syndrome |
| TYPE 2 DM | -caused by insulin deficiency; insulin resistance -most common type (90%) -GOLD - metformin -lifestyle change, weight loss, no smoking, decrease alcohol, exercise, oral drug therapy, insulin |
| DIABETES MELLITUS | complex disorder that affects carbohydrate, protein & fat metabolism (6th leading cause of death in the U.S.) |
| GESTATIONAL DIABETES | -women who show abnormal glucose tolerance during pregnancy -7% of all women -subsides after delivery |
| blood glucose of 224 = | 9U |
| blood glucose of 88 = | zero, none |
| blood glucose of 350 = | 12U |
| blood glucose of 157 = | 7U |
| Blood Glucose Sliding Scale | ^100 = 5U ^150 = 5U + 2U = 7U ^200 = 5U + 4U = 9U ^250 = 5U + 5U = 10U ^300 = 5U + 7U = 12U |
Created by:
Smccunn
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