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Diabetes Mellitus

Pharmacology Mod B - Diabetes Mellitus

RAPID-ACTING INSULIN -NovoLog (aspart) -Humalog (lispro) -Apidra (glulisine)
SHORT-ACTING INSULIN -Humulin R (human) -Novolin R (human)
INTERMEDIATE-ACTING INSULIN -Humulin N (human) -Novolin N (human)
LONG-ACTING INSULIN -Lantus (glargine) -Toujeo (glargine) -Levemir (detemir)
NovoLog (aspart) ONSET - rapid 0.2 - 0.33
Humalog (lispro) ONSET - rapid 0.2 - 0.33
Apidra (glulisine) ONSET - rapid 0.2 - 0.33
NovoLog (aspart) PEAK - rapid 1 - 3
Humalog (lispro) PEAK - rapid 0.5 - 2.5
Apidra (glulisine) PEAK - rapid 0.5 - 1.5
NovoLog (aspart) DURATION - rapid 3 - 5
Humalog (lispro) DURATION - rapid 3 - 6.5
Apidra (glulisine) DURATION - rapid 4 - 5
Humulin R (human) ONSET - short 0.5 - 1
Novolin R (human) ONSET - short 0.5 - 1
Humulin R (human) PEAK - short 2.5 - 5
Novolin R (human) PEAK - short 2.5 - 5
Humulin R (human) DURATION - short 5 - 10
Novolin R (human) DURATION - short 8
Humulin N (human) ONSET - intermediate 1 - 2
Novolin N (human) ONSET - intermediate 1 - 2
Humulin N (human) PEAK - intermediate 4 - 12
Novolin N (human) PEAK - intermediate 4 - 12
Humulin N (human) DURATION - intermediate 16 - 28
Novolin N (human) DURATION - intermediate 24
Lantus (glargine) ONSET - long 1.1
Toujeo (glargine) ONSET - long 1.1
Levemir (detemir) ONSET - long 1
Lantus (glargine) PEAK - long n/a
Toujeo (glargine) PEAK - long n/a
Levemir (detemir) PEAK - long n/a
Lantus (glargine) DURATION - long 24
Toujeo (glargine) DURATION - long 24
Levemir (detemir) DURATION - long up to 24
HYPOGLYCEMIA -abnormal low blood glucose level -below 70 mg/dL -"COLD & CLAMMY = NEED SOME CANDY"
HYPERGLYCEMIA -excess of glucose in the bloodstream -above 100 mg/dL -"HOT & DRY = SUGAR HIGH"
TYPE 1 DM -caused by autoimmune destruction of the beta cells -beta needs insulin -insulin therapy -diabetic ketoacidosis and hyperosmolar non-ketonic syndrome
TYPE 2 DM -caused by insulin deficiency; insulin resistance -most common type (90%) -GOLD - metformin -lifestyle change, weight loss, no smoking, decrease alcohol, exercise, oral drug therapy, insulin
DIABETES MELLITUS complex disorder that affects carbohydrate, protein & fat metabolism (6th leading cause of death in the U.S.)
GESTATIONAL DIABETES -women who show abnormal glucose tolerance during pregnancy -7% of all women -subsides after delivery
blood glucose of 224 = 9U
blood glucose of 88 = zero, none
blood glucose of 350 = 12U
blood glucose of 157 = 7U
Blood Glucose Sliding Scale ^100 = 5U ^150 = 5U + 2U = 7U ^200 = 5U + 4U = 9U ^250 = 5U + 5U = 10U ^300 = 5U + 7U = 12U
Created by: Smccunn