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Pulm Disease Exam 4
SPC Pulmonary Disease Exam 4 Ch. 26 Interstitial Lung Disease
| Question | Answer |
|---|---|
| Anatomic alterations of ILD may involve what? | 1. Bronchi 2. Alveolar walls 3. Adjacent alveolar spaces |
| In severe cases of ILD, intense inflammation leads to what? | 1. Pulmonary Fibrosis 2. Granulomas 3. Honeycombing 4. Cavitation |
| Major pathologic changes associated with chronic ILD are? | 1. Fibrotic thickening of bronchioles, alveolar ducts, & alveoli 2. Granulomas 3. Honeycombing 4. Fibrocalcific Pleural Plaques |
| How many pulmonary disorders are classified as ILD? | >180 |
| Pneumoconiosis | Occupational, Environmental, & Therapeutic exposure to causes of ILD |
| Common sources associated with asbestos fibers? | 1. INSULATION 2. Automobile undercoating 3. Clutch casings 4. Firefighting suits |
| Inorganic exposure to ILD? | 1. Asbestosis 2. Coal Dust 3. Silica (sand) 4. Beryllium |
| T/F Pleural calcification is common and diagnostic in patients with asbestos exposure history. | True |
| Pulmonary accumulation of large amounts of coal dust causes? | Coal Workers Pneumoconiosis (CWP) |
| Coal Workers Pneumoconiosis (CWP) is also known as? | Coal Miners Lung or Black Lung |
| Complicated CWP is characterized by what? | Areas of fibrotic nodules >1cm in diameter. |
| Fibrotic changes in CWP are usually caused by? | Silica (sand) |
| Silcosis is also known as what? | Grinder's Disease or Quarts Silcosis |
| Silcosis is caused by what? | chronic inhalation of crystalline, free silica, or silicon dioxide particles |
| Silica is found in what? | Sandstone, Quartz, Flint, Granite, Hard rocks and clays |
| Common occupations associated with silica exposure? | SANDBLASTING, ceramics, rock mining, drilling |
| Additional Inorganic causes of Interstitial Lung Disease? | Sidrosis (Iron) & Talcosis (paper, rubber, plastic, & ceramic workers) |
| Organic exposure to ILD? | Hypersensitivity Pneumonitis 1. Moldy Hay 2. Moldy Sugar Cane 3. Cheese 4. Wood Pulp |
| Common forms of Hypersensitivity Pneuomontitis? | Farmers Lung, Aspergillus, Dyssinosis, Humidifier Lung |
| What is not a hypersensitivity pneumontitis? | Histosytosis |
| Systemic diseases associated with ILD? | 1. Connective Tissues 2. Rheumatoid Arthritis 3. Sjogrens Syndrome 4. Polymyositis-Dermatomyositis 5. Systemic Lupus Erythmatosus 6. Sarcoidosis |
| What is scleroderma? | Characterized by chronic hardening and thickening of the skin causes by new collagen formation. |
| What is Systemic Lupus Erythematosus? | Multisystem disorder that mainly involves the joints and skin, lungs being 50%-70% of cases. |
| Sarcoidosis is? | Characterized by the formation of tubercles of non-necrotizing epithelioid. (noncaseating granulomas) |
| Clinical hallmarks of sarcoidosis is an increase of all 3 immunoglobulins? | IgM, IgG, & IgA |
| Sarcoidosis is common among who? | African-Americans, from 10-40 years of age, women more than men |
| Idiopathic Interstitial Pneumonias? | 1. Idiopathic Pulmonary Fibrosis 2. Cryptogenic Organizing Pneumonia (BOOP) 3. Lymphocytic Interstitial Pneumonia |
| Diagnosis of Idiopathic Interstitial Pneumonias? | Generally confirmed by an open biopsy |
| What does Hamman-Rich Syndrome mean? | Rapidly progressive disorder |
| What is pulmonary vasculitides? | Heterogeneous group of pulmonary disorders characterized by inflammation and destruction of the pulmonary vessels. |
| Major disorder of pulmonary vasculitides? | Churg-Strauss |
| What is good pastures syndrome? | Disease of unknown cause, that involves two organ systems lungs and kidneys. |
| What happens to the lung volumes with ILD? | All decrease |
| Chest radiographs of ILD? | 1. Honeycombing 2. Cavity Formation 3. Granulomas |
| Best management for ILD? | Corticosteroids |