Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Autonomic NS Drugs
Generic name, uses/indications, and main site/mode of action
| Name (generic) | Uses/Indications | Site or Mode of Action |
|---|---|---|
| Phenylephrine | severe hypotension, decongestant, mydriasis | α-1 agonist |
| oxymetazoline | decongestant | α-1 agonist |
| Clonidine | hypertension, migraine, ADHD, glaucoma | α-2 agonist |
| Dobutamine | heart failure -pressor and ionotrophic support | β-1 agonist |
| Salbutamol | asthma, premature labor | β-2 agonist |
| terbutaline | asthma | β-2 agonist |
| salmeterol | asthma, not for acute bronchspasm | β-2 agonist |
| Adrenaline (Epinephrine) | anaphylaxis, cardiac resuscitation, given with local anesthetics | α/β agonist |
| Isoprenaline | asthma, cardiac resuscitation | β agonist |
| Prazosin | hypertension | α-1 antagonist |
| doxazocin | hypertension, benign prostatic hypertrophy | α-1 antagonist |
| Yohimbine | No clinical use, supposedly an aphrodisiac | α-2 antagonist |
| Atenolol | hypertension | β-1 antagonist |
| metoprolol | hypertension, compensated heart failure | β-1 antagonist |
| Labetalol | hypertension in pregnancy | α/β antagonist |
| propranolol | hypertension, angina, dysrhythmias, migraine | β antagonist |
| Amphetamine | Appetite suppressant, ADHD, narcolepsy | ↑NA, ↓uptake 1. MAOI, CNS stimulant |
| Ephedrine | Decongestant | ↑NA |
| α-Methyl-p-tyrosine | Occasionally in pheochromocytoma | Inhibits tyrosine hydroxylase |
| Carbidopa | Parkinsons – in conjunction with leva-DOPA to ↓peripheral effects | Inhibits DOPA-decarboxylase |
| Methyldopa | Hypertension in pregnancy | False transmitter precursor |
| Reserpine | Essential hypertension, schizophrenia | Depletes NA stores by inhibiting vesicular uptake of NA |
| Imipramine | Depression | Blocks uptake 1 |
| Cocaine | Local anesthetic (rarely) | Blocks uptake 1, local anesthetic, CNS stimulant |
| Atropine | Reduces gastrointestinal motility, Adjunct for anaesthesia (reduced secretions, bronchodilatation), Anticholinesterase poisoning, Bradycardia, inhibition of SLUD | non-selective muscarinic antagonist |
| Hyoscine | Motion sickness | non-selective muscarinic antagonist |
| Ipratropium | Bronchodilator | non-selective muscarinic antagonist |
| Cyclopentolate | Ophthalmic use to produce mydriasis and cycloplegia (as eye drops) (Long acting) | M4 antagonist |
| Tropicamide | Ophthalmic use to produce mydriasis and cycloplegia (as eye drops)(Short acting) | M4 antagonist |
| Pirenzipine | Reduces gastric acid secretion by action on ganglion cells, Peptic ulcer | M1 antagonist |
| Benzhexol | Parkinsonism, esp to counteract movement disorders caused by antipsychotics. | M1 antagonist |
| Pilocarpine | Glaucoma, angle-closure, Glaucoma, open-angle, xerostomia | Muscarinic agonist |
| Timolol | Hypertension, essential, Glaucoma, open-angle, myocardial infarction, migraine, headache prophylaxis | β-Adrenoceptor antagonist |
| Acetazolamide | Glaucoma, edema, mountain sickness, unlocalized and absence seizures | Carbonic anhydrase inhibitor |
| Pancuronium | Muscle relaxant in anesthesia | Nicotinic antagonist - block transmission at NMJ |
| Trimetaphan | Blood pressure lowering in surgery (rarely used) | Nicotinic antagonist that blocks trasmission at autonomic ganglia |
| Botulinum Toxin | Blepharospasm, Dystonia, cervical, Glabellar lines, Strabismus | Blocks ACh release |
Created by:
golfspy
Popular Pharmacology sets