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Platinum Analogs

Important fun facts about the platinum analogs

QuestionAnswer
How was cisplatin discovered? when used in as an electrode study, evaluating electricity's effect on cancer cells
What is the cumulative dose limiting toxicity of cisplatin? Renal toxicity
What is the cumulative dose limiting toxicity of oxaliplatin? neurotoxicity
How is carboplatin dosed? Calvert formula
What toxicity guides carboplatin dosing Thrombocytopenia
What platinum analog has the highest emetogenic potential? Cisplatin
What best describes the class/MOA of platinum analogs? non-traditional alkylating agents
Created by: vadam0