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Chpt.15 T&D
Therapeutic Agents for the Nervous System: Terms and Definitions
Term | Definition |
---|---|
Alzheimer's disease (AD) | A progressive form of dementia that affects memory, thinking, and behavior |
Attention deficit/hyperactivity disorder (ADHD) | A physiological brain disorder that affects the ability to engage in quiet, passive activities or to focus one's attention; attributable to an imbalance of neurotransmitters in the brain |
Autonomic nervous system | A branch of the nervous system that carries out “automatic” bodily functions; it is composed of the sympathetic and parasympathetic systems |
Blood-brain barrier (BBB) | A barrier that exists in the brain as a result of special permeability characteristics of the capillaries that supply brain cells; these capillaries prevent certain solutes or chemicals from being transferred from the blood to the brain |
Bradykinesia | Slowed movement |
Brainstem | A section of the brain consisting of the medulla oblongata, pons, and midbrain, which connect the forebrain and cerebrum to the spinal cord |
Central nervous system (CNS) | Consists of the brain and spinal cord; it acts to coordinate sensory and motor control of body functions |
Cerebellum | A structure located posterior to the pons and medulla oblongata; it is responsible for posture, balance, and voluntary muscle movement |
Cerebrospinal fluid (CSF) | Clear watery fluid that is continually produced and absorbed that flows in the ventricles of the brain and around the surface of the brain and spinal cord |
Epilepsy | A brain disorder marked by repeated seizures over time |
Extrapyramidal symptoms (EPS) | Often result from taking antipsychotic medications and include parkinsonism, dystonia, and tremors |
Hemorrhagic stroke | A stroke caused by the rupture of a blood vessel in the brain |
Homeostasis | The tendency of the body to maintain stability, such as with body temperature |
Insomnia | Difficulty falling or staying asleep |
Ischemic stroke | A stroke caused by blockage of a blood vessel in the brain |
Multiple sclerosis (MS) | An autoimmune disorder that affects nerves in the CNS; it leads to impaired motor function |
Myasthenia gravis | A neuromuscular disorder leading to weakness of the skeletal muscles |
Neuron | The basic building block and cell of the nervous system |
Parasympathetic nervous system (PSNS) | A division of the autonomic nervous system that functions during restful situations |
Parkinson's disease (PD) | A movement disorder with the classic symptoms of tremor, rigidity, bradykinesia, and postural instability |
Peripheral nervous system (PNS) | The division of the nervous system outside the brain and spinal cord |
Polyneuropathy | A neurological disorder that occurs when many nerves throughout the body malfunction; it can be associated with painful neuropathy |
Psychosis | A mental illness characterized by loss of contact with reality; it may be a true mental illness, due to an underlying medical condition (e.g., dementia, drug withdrawal syndromes), or induced by substances |
Schizophrenia | A disorder characterized by inappropriate emotions and unrealistic thinking |
Somatic nervous system | The motor neurons of the peripheral nervous system that control voluntary actions of the skeletal muscles and provide sensory input (touch, hearing, sight) |
Sympathetic nervous system (SNS) | A division of the autonomic nervous system that functions during stressful situations; the “fight or flight” part of the autonomic nervous system |
Tardive dyskinesia (TD) | A type of dyskinesia attributed as a potential side effect of taking dopamine antagonists such as phenothiazines or other medications (e.g., metoclopramide); the symptoms may continue even after discontinuation of the offending drug |