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PHARMACOLOGY
MODULE 1 KEY TERMS
| Term | Definition |
|---|---|
| Absorption | the movement of a drug into the bloodstream. |
| Adverse Effect | any unexpected or dangerous reaction to a drug |
| Agonist | a chemical that binds to a receptor and activates the receptor to produce a biological response |
| bioavailability | a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs |
| biotechnology | the use of living cells and cell materials to research and produce pharmaceutical and diagnostic products that help treat and prevent human diseases |
| biotransformation | chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body |
| bolus | the administration of a discrete amount of medication, drug or other compound in order to raise its concentration in blood to an effective level. |
| Contraindication | a specific situation in which a drug, procedure, or surgery should not be used because it may be harmful to the person |
| distribution | a branch of pharmacokinetics which describes the reversible transfer of a drug from one location to another within the body. |
| duration | This is the period of time required for the concentration or amount of drug in the body to be reduced by one-half. |
| emulsion | a thermodynamically unstable system consisting of at least two immiscible liquid phases one of which is dispersed as globules in the other liquid phase stabilized by a third substance called emulsifying agent |
| enteral | administration involves the esophagus, stomach, and small and large intestines |
| excretion | process by which a drug is eliminated from an organism either in an unaltered form (unbound molecules) or modified as a metabolite |
| hypersensitivity | An excessive or abnormal sensitivity to a substance |
| idiosyncratic effect | are drug reactions that occur rarely and unpredictably amongst the population. |
| indication | a condition which makes a particular treatment or procedure advisable |
| local effect | The impact of a therapeutic agent on specific tissues rather than on the whole body, esp. on those tissues where the agent is absorbed, metabolized, or most chemically active. |
| onset | the duration of time it takes for a drug's effects to come to prominence upon administration |
| parenteral | Taken into the body or administered in a manner other than through the digestive tract, as by intravenous or intramuscular injection |
| pharmacodynamics | Pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. |
| pharmacokinetics | the study of the bodily absorption, distribution, metabolism, and excretion of drugs. |
| plasma protein binding | A drug's efficiency may be affected by the degree to which it binds to the proteins within blood plasma |
| reconstituted | The restitution or return to an original state of a substance, or combination of parts to make a whole |
| side effect | an effect, whether therapeutic or adverse, that is secondary to the one intended |
| solubility | the property of a solid, liquid, or gaseous chemical substance called solute to dissolve in a solid, liquid, or gaseous solvent to form a homogeneous solution of the solute in the solvent. |
| solution | a liquid preparation of one or more soluble chemical substances, which are usually dissolved in water. |
| suspension | the state of a substance when its particles are mixed with but undissolved in a fluid or solidb |
| synergist | an agent that increases the effectiveness of another agent when combined with it |
| systemic effect | affecting the whole body, or at least multiple organ systems |
| topical | something applied to the surface of the body |
| controlled substances | a drug or chemical whose manufacture, possession, or use is regulated by a government |
| narcotics | a drug (as codeine, methadone, or morphine) that in moderate doses dulls the senses, relieves pain, and induces profound sleep but in excessive doses causes stupor, coma, or convulsions |
| DEA | Drug Enforcement Administration |
| FDA | The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments |
| The Joint Commission | an independent, not-for-profit group in the United States that administers voluntary accreditation programs for hospitals and other healthcare organizations |
| OTC | Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may only be sold to consumers possessing a valid prescription. |
| PDR | Physicians' Desk Reference |
| USP-NF | The United States Pharmacopeia and The National Formulary (USP–NF) is a book of public pharmacopeial standards for chemical and biological drug substances, dosage forms, compounded preparations, excipients, medical devices, and dietary supplements. |