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Antimicrobials
Anitvirals, Other drugs for RSV, PCP
| Question | Answer |
|---|---|
| What are the two antiviral agents mentioned in class? | Acyclovir, Valacyclovir |
| Valacyclovir is a prodrug of what? | Acyclovir |
| What virus is Valacyclovir indicated for? | Herpes simplex Virus |
| Where is the Herpes virus commom? | ICU |
| What are the reasons for complications in treating viruses? | Attacking virus could harm the host, No symptoms when virus replicates, Viruses are mutants |
| What other drugs can be used to treat RSV? | RSV-IGIV, Palivizumab/Synagis |
| Who is indicated for Respigam? | Children at risk of RSV: <24mos w/history of BPD and premature birth |
| What is the mode of action for Respigam? | Passive immunity - exposure to antibody of RSV |
| What is the mode of action for Palivizumab/Synagis? | Prevents viral replication |
| What does PCP stand for? | Pneumocystis Carinii Pneumonia |
| Who is most at risk for PCP? |