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Beta Agonists 3

Indications, Mode of Action, Side Effects

QuestionAnswer
Beta Agonists Airway obstruction in asthmas and COPD
Albuterol, Levalbuterol, Metaproterenol Acute airflow obstruction
Salmeterol, Formoterol, Arformetorol Maintenance bronchodilation, control bronchospasm
Racemic Epi Reduce AW swelling after extubation or epiglottitis, croup, or control AW bleeding
What is the mode of action of adrenergic drugs? stimulation of Beta 2 receptors located in bronchial smooth muscle`
What are the effects of Alpha receptor stimulation? Vasoconstriction in upper AW, decongestion
What are the effects of Beta 1 receptor stimulation? Increased heart conductivity, heart rate, and contractile force
What are the effects of Beta 2 receptor stimulation? Relaxation of bronchial smooth muscle, mucociliary clearance, some inhibition of inflammation
What are the side effects of Beta adrenergic bronchodilators? Tachycardia, nervousness, tremors, nausea
Terbutaline stop contractions in premature labor
What is responsible for the breakdown of Beta agonist? COMT
What breaks down C3'5'AMP to 5 AMP? Phosphodiesterase
How does bronchodilation occur? Attachment to Beta 2 receptors - Gs protein - adenylyl cyclase - C3'5'AMP
Created by: kreblackwell