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Car/Pul Final Exam

SPC Cardiopulmonary Physiology Final Exam Unit 5 Review

Anatomical location of Peripheral Chemoreceptors? Aortic Arch & Carotid Sinus
Which nerve innervates the carotid bodies? Glossopharyngeal (IX)
Which nerve innervates the aortic bodies? Vagus (X)
The chemical stimuli for Peripheral Chemoreceptors? Low O2 Tension <60 & Low pH
Anatomical location of Central Chemoreceptors? Ventrolateral Surface of the medulla immersed in CSF
The chemical stimuli for Central Chemoreceptors? High CO2 Tension & Low pH
How is ventilation effected in chronic respiratory acidosis? 1. HCO3 increases in CSF and the central chemoreceptors are obtunded (dull). 2. Low PaO2 stimulated the peripheral chemoreceptors establishing hypoxic drive.
How is ventilation effected in severe metabolic acidosis (Ketoacidosis)? H+ stimulate the central and peripheral chemoreceptors causing a Kussmaul's breathing pattern and PaCO2 drop in the 20's
What is the control center for ventilation? Cerebral Cortex
VE Changes: PaCO2 With normal PaO2, VE increases 3L/min for each mmHg rise in PACO2.
VE Changes: PaO2 VE increases dramatically when the PaO2 falls below 60mmHg.
VE Changes: pH Acute Acidosis stimulates Peripheral Chemoreceptors & VE increases. The lower the pH, the greater the VE increases.
Created by: Langhout1418