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Car/Pul Final Exam

SPC Cardiopulmonary Physiology Final Exam Unit 4 Review

QuestionAnswer
High V/Q Ratio & Location? 4/4=1.0 Apical Region Of Upper Right Lung
Low V/Q Ration & Location? 3/5=0.6 Basal Region Of Lower Right Lung
Disease/Disorders of High V/Q? (Deadspace) 1. Pulmonary Emboli 2. Circulatory Shock
Disease/Disorders of Low V/Q? (Shunt) 1. Atelectasis 2. Pulmonary Edema 3. Pneumonia
Fick's Law: Gas diffusion across a tissue (A/C) membrane is DIRECTLY PROPOSTIONAL to what? 1. Membrane Surface Area 2. Gas Pressure Gradient 3. Gas's Pressure Coefficient
Fick's Law: Gas diffusion across a tissue (A/C) membrane is INVERSELY PROPOSTIONAL to what? 1. Membrane Thickness
Hemoglobin "A" is protein base composed of what? 1. 2 Alpha Polypeptide Chains 2. 2 Beta Polypeptide Chains 3. 4 Heme (Iron) Groups (each heme combines w/ an O2 molecule)
What is P50? The partial pressure required to saturate the Hb to a 50% level
Normal P50? 27mmHg
Decrease P50? <20mmHg Left Shift: (Load) O2 Loading Easier in Lung O2 Unloading Harder in Tissue
Increase P50? >35mmHg Right Shift: (Release) O2 Loading is Harder in Lung O2 Unloading is Easier in Tissue
P50 Left Shift Factors? Increase pH (Alkalemia) 1. Decrease CO2 2. Hypothermia 3. Decrease 2,3 DPG
P50 Right Shift Factors? Decrease pH (Acidemia) 1. Increase CO2 2. Hyperthermia 3. Increase 2,3 DPG
What are the 3 altered Hemoglobin's? 1. Methemoglobin 2. Carboxyhemoglobin 3. Fetal Hemoglobin
What is Methemoglobin (MHb)? A congenital or chemically induced alteration of the HEME portion of Hb: Decrease P50
What is Carboxyhemoglobin (HbCO)? Carbon Monoxide (CO) poisoning or cigarette smoking: Decrease P50
What is Fetal Hemoglobin (HbF)? Seen in fetus and neonate, converted to HbA by 6mo. Altered 2,3 DPG binding noted with HbF
Formula for DO2? C.O. x (CaO2 x 10) = DO2
Normal Value for DO2? 1000ml/min
Formula for O2 Consumption? C.O. (Ca-vO2 x 10) = O2 Consumption
Normal Value for O2 Consumption? 250ml/min
4 factors that increase O2 Consumption? 1. Exercise 2. Seizures 3. Shivering 4. Hyperthermia
3 factors that decrease O2 Consumption? 1. Peripheral Shunting 2. Cyanide Poisoning 3. Hypothermia
Normal Value for Ca-vO2? 20-15=5ml O2/dL
6 factors that increase Ca-vO2? 1. Decrease C.O. 2. Increase O2 Consumption 3. Exercise 4. Seizures 5. Shivering 6. Hyperthermia
5 factors that decrease Ca-vO2? 1. Increase C.O. 2. Decrease O2 Consumption 3. Peripheral Shunting 4. Cyanide Poisoning 5. Hypothermia
Formula for O2ER? (CaO2-CvO2)/CaO2) = O2ER
6 factors that increase O2ER? 1. Decrease C.O. 2. Increase O2 Consumption 3. Exercise 4. Seizures 5. Shivering 6. Hyperthermia
5 factors that decrease O2ER? 1. Increase C.O. 2. Decrease O2 Consumption 3. Peripheral Shunting 4. Cyanide Poisoning 5. Hypothermia
Formula for Qs/Qt? (CcO2 - CaO2)/(CcO2 - CvO2) = Qs/Qt
Normal Qs/Qt? <10%
Mild Qs/Qt? 10-20%
Moderate Qs/Qt? 20-30%
Severe Qs/Qt? >30%
Created by: Langhout1418