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Bugs + Drugs 2

General spectra + resistance

DrugSpectrumTreat special bugs?MetabolismAE's
Ampicillin/Amoxicillin Gram + and - Borrelia; Listeria; S. pneumo for OM/Sinusitis; + AG = Enterococcus Renal Allergic
Methicillin, Nafcillin, Oxacillin Gram + S. aureus Hepatic Hepatitis
Piperacillin Gram + and - Pseudomonas, Bacteroides Renal Nephritis, (neutro)penias
Carbapenam (imipenam) Broadest spectrum of ß lactams (everything except fungi) Pseudomonas, Bacteroides Renal
1st generation Cephs Gram + Renal
2nd generation Cephs Gram + and - Renal
3rd generation Cephs Gram + and -; no staphylococcus coverage Pseudomonas (Ceftazidime), N. meningitidis, Chlamydia Both
Aztreonam (monobactam) Gram - Renal
Vancomycin Gram + MRSA, S. epidermidis, S. pneumo if PCN resistant strain, C. difficile Renal Red person syndrome (histamine)
Daptomycin Gram + VRE, MRSA, C diff, Enterococcus Renal CK increase, myopathy
TMP/SMX Almost everything Nocardia, MRSA Hepatic Rash; need folinic acid supplement @ high dose
Fluoroquinolones (Ciprofloxacin) Almost everything Bacillus anthracis Renal Sz @ high dose
Metronidazole Anaerobes, parasites C. difficile, Bacterioides Hepatic Like antabuse
Penicillin G Gram +, Spirochetes Most kinds of strep!, Clostridia, Spirochetes, Actinomyces Renal Allergic rxn
Clindamycin 1. GPC 2. Anaerobes: B. fragilis, C. perfringens 3. parasite 4. fungus: PCP Bacillus cereus, Clostridia, Bacteroides Hepatic Pseudomembranous colitis
Created by: eemolee27
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