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Pharmacy Technician
Peripheral Nervous System Drugs
| Question | Answer |
|---|---|
| What are local anesthetics used for? | Minor surgery |
| How do local anesthetics work? | Blocks conduction of impulses along nerves and prevents the sensation of pain from reaching the brain. |
| What are the side effects of local anesthetics? | Allergies |
| What are Lidocaine (Xylocaine), Benzocaine (Anbesol, Orajel, and Solarcaine), Tetracaine (Pontocaine), and Cocoain (Schedule I) examples of? | Local anesthetic drugs |
| What are Parasympathomemetic (Cholinergic) Agents used for? | *Glaucoma *Bladder problems *Gastrointestinal problems *Alzheimer's Disease |
| How do Parasympathomemetic (Cholinergic) Agents work? | *Salivation, lacrimation, urination, defecation, enhance the actions of the parasympathetic nervous system, opposes the effects of the sympathetic nervous system. *May be direct action on cholinergic receptors or indirect through inhibition of enzymes |
| What are the side effects of Parasympathomemetic (Cholinergic) Agents? | *Diarrhea *Bradycardia *Hypotension |
| What are Pilocarpine (Pilocar) and Carbochol (Miostat) and what are they used for? | Parasympathomemetic (Cholinergic) Agent that are used for glaucoma. |
| What is Bethanechol (Urecholine) and what is it used for? | Parasympathomemetic (Cholinergic) Agent used for bladder problems. |
| What are Donepezil (Aricept) and Memantine (Namenda) and what are they used for? | Parasympathomemetic (Cholinergic) Agent used for Alzheimer's Disease |
| What are Parasympathomemetic (Anti-cholinergic) Agents used for? | *Anti-spasmodic *Anti-Parkinson's *Bronchial Disorders *Eye exams *Motion sickness *Overactive bladder |
| How do Parasympathomemetic (Anti-cholinergic) Agents work? | Inhibit or reverse the actions of the parasympathetic nervous system and bind with cholinergic receptors and prevent binding of acetylcholine (they are antagonists). |
| What are the side effects of parasympathomemetic (Anti-cholinergic) Agents? | *Urinary retention *Tachycardia *Dry mouth *Constipation *Mydriasis (pupil dilation) |
| What are Atropine and Benztropine (Cogentin)? | Parasympathomemetic (Anti-cholinergic) Agent |
| What is Scopolamine and what is it used for? | Parasympathomemetic (Anti-cholinergic) Agent used for motion sickness. |
| What is Oxybutynin (Ditropan) and what is it used for? | Parasympathomemetic (Anti-cholinergic) Agent used for overactive bladder. |
| What are Neuromuscular Blocking Agents used for? | Pre-operational muscle relaxant |
| How do Neuromuscular Blocking Agents work? | *Block transmission of nerve impulses to skeletal muscles resulting in paralysis. *There is a narrow therapeutic index- when used, life sustaining respiratory support equipment must be available. |
| What are the side effects of Neuromuscular Blocking Agents? | *Respiratory distress *Cardiac distress |
| What are Cisatracurium (Nimbrex), Succinycholine (Anectine), Pancuronium (Pavulon), and Vecuronium (Norcuron) examples of? | Neuromuscular Blocking Agents |
| What are Adrenergic Antagonists (blockers)/ Sympatholytic Agents used for? | *Hypertention *Heart disease *Migraine Headaches |
| How do Adrenergic Antagonists (blockers)/ Sympatholytic Agents work? | Oppose the action of the natural messengers, epinephrine and norepinephrine, as their receptor sites. |
| What are the side effects of Adrenergic Antagonists (blockers)/ Sympatholytic Agents? | *Dizziness *Syncope *Nasal Stuffiness |
| What are Propanolol (Inderal), Atenolol (Tenormin), Metaprolol (Lorpressor), Nadolol (Corgard), Timolol (Blacadren), Acebutolol (Sectral), Betaxolol (Betoptic), and Penbutolol (Levatol) examples of? | Adrenergic Antagonists (blockers)/ Sypatholytic Agents-BETA BLOCKERS |
| B-1 receptors effect what organ? | Heart |
| B-2 receptors effect what organ? | Lungs |
| What is Ergotamine and what is it used for? | Adrenergic Antagonists (blockers)/ Sympatholytic Agent- ALPHA BLOCKER used for migraines |
| What is Prazosin (Minipress) and what is it used for? | Adrenergic Antagonists (blockers)/ Sympatholytic Agent- ALPHA BLOCKER used for blood pressure |
| What is Terazosin (Hytrin) and what is it used for? | Adrenergic Antagonists (blockers)/ Sympatholytic Agent- ALPHA BLOCKER used for blood pressure |
| What is Tamsulosin (Flomax) and what is it used for? | Adrenergic Antagonists (blockers)/ Sympatholytic Agent- ALPHA BLOCKER used for enlarged prostate |
| What is Labetolol (Trandate) and what is it used for? | Adrenergic Antagonists (blockers)/ Sympatholytic Agent- ALPHA BETA BLOCKER used for blood pressure |
| What are Indirect Acting Sympathomimetic Agents used for? | Facilitate the release of norepinephrine or block the re-uptake of norepinephrine in the neuronal membrane. |
| How do Indirect Acting Sympathomimetic Agents work? | Increase the release of norepinephrine |
| What are the side effects for Indirect Acting Sympathomimetic Agents? | *Habitual abortion *Blurred vision *Irritability *Insomnia *Nausea *Loss of appetite Dizziness *Tachycardia *Trouble Sleeping |
| What is Adderall and what are its side effects? | Schedule II Amphetamine Indirect Acting Sympathomimetic Agent. Can cause; *HA *Blurred vision *Irritability *Insomnia *Nausea *Loss of appetite |
| What is Dextrostat, Dexedrine and what are its uses and side effects? | Schedule II Amphetamine Indirect Acting Sympathomimetic Agent. Used for; *ADHD *Narcolepsy Side effects: *HA *Dizziness *Tachycardia |
| What is Methylphenidate (Ritalin) and what are its uses and side effects? | Schedule II Amphetamine Indirect Acting Sympathomimetic Agent. Used for; *ADD/ADHD Side effects; *HA *Insomnia *Nausea *Trouble sleeping |
| What are Sympathomimetic Agents (Direct) used for? | *HTN *Shock *Heart block *Ashma *Depression -Effects are complex and depend on where drugs take effect |
| How do Sympathomimetic Agents (Direct) work? | Depends on where the drug takes effect |
| What are the side effects of Sympathomimetic Agents (Direct)? | *HTN *Increased heart rate *Depeds where the drug takes effect |
| What is Clonidine (Catapres) and what is it used for? | Sympathomimetic Agent (Direct) and legend used for blood pressure |
| What is Dobutamine (Dobutrex) and what is it used for? | Sympathomimetic Agent (Direct) and legend used for increasing cardiac output |
| What is Levalbuterol (Xopenex) and what is it used for? | Sympathomimetic Agent (Direct) and legend used for breathing |