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Pharmacy Technician
Central Nervous System Drugs
| Question | Answer |
|---|---|
| What is the use of a smoking deterrent? | To aid in stopping smoking |
| What is the mechanism of action of Varenicline (chantix)? | Mimics the action of nicotine on the brain and can help in both easong nicotine withdrawal symptoms and blocking the reinforcing effects of nicotine if smoking is resumed. |
| What is the mechanism of Bupropion (Wellbutrin and Zyban)? | Used to help people stop smoking by reducing cravings and other withdrawal effects. |
| What are the side effects of nicotine alternative smoke deterrents? | *Nausea *Vomiting *Headache *Flatulence *Insomnia *Abnormal dreams *Changes in taste perception |
| What is the mechanism of action of a nicotine replacement smoke deterrent? | Releases nicotine into the body to prevent withdrawal. |
| What are the side effects of nicotine replacement smoke deterrents? | *Dizziness *Drowsiness *Irritability *Headache *Sleep distrubances *Vivid dreams *Mild hallucinations *Depression |
| What are nicotine patches (Nicoderm CQ) and Nicotine Gum (Nicorette Gum) examples of? | Nicotine replacement smoke deterrents. |
| What are Antiparkinson's Agents used for? | To treat the shaking, rigidity, salvation, and slowing of initial movements associated with Parkinson's Disease. |
| How do AntiParkinson's Agents work? | Restoring the balance between the hormones acetylcholine and dopamine (Parkinson's is caused by a decreased dopamine level) |
| What are side effects of Antiparkinson's Agents? | *Dry mouth *Blurred vision *Consitipation *Hallucination *Memory impairment *Dizziness *Insomnia *Nervousness *Irritability *Confusion *Nausea *Vomiting *Arrythmias *Fatigue |
| What are Levodopa/Carbidopa (Sinemet) used for? | Antiparkinson's Agent considered the "gold standard" in treatment. |
| What are CNS stimulants used for? | *Improve mental function *Elevate moods *Overcome fatigue *Produce a general feeling of well being *Narcolepsy *Hyperkinesis (ADHD in children) *Anorexiants (management of obesity) |
| What is the mechanism of action of amphetamines? | Stimulate activity and are mediated by the release of Norepinephrine and Dopamine in the brain |
| What is the mechanism of action of Pemoline and methylphenidates? | No action is known. |
| What are the side effects of CNS stimulants? | *Dependence *Increased blood pressure *Increased Resipiratory Rate *Upset stomach |
| What are caffeine, methylphenidate (ritalin), dextroamphetamine (dexadrine), and adderall (amphetamine mixture) examples of? | CNS stimulants. |
| What are antianxiety agents (anxiolytics) used for? | *Relieve nervousness and tension in normal or neurotic patients. *Have muscle relaxing capabilities. *Some have anticonvulsant activity. |
| What is the mechanism of action of Benzodiazepines? | Bind to and affecting certain neurotransmitters in the brain. |
| What is the mechanism of action of Buspirone? | Has an affect on th seratonin and dopamine receptors. |
| What are side effects of antianxiety agents? | *Drowsiness *Dizziness *Fatigue *Abrupt termination of high doses can cause coma, convulsions, and death. |
| What are Alprazolam (Xanax), Lorazepam (Ativan), Diazepam (Valium) and Midazolam (Versed) examples of? | Benzodiazepines used to treat anxiety. |
| What are Buspirone (BuSpar) and Doxepine (Sinequan) examples of? | Non-benzodiazepine medications used to treat anxiety. |
| What is the Alzheimer's Disease medications mechanism of action? | NMDA (N-methyl-D-aspartate) Receptor Antagonist |
| What are side effects of Alzheimer's Disease medications? | *Dizziness *Confusion *Nausea *Insomnia *Agitation *Coughing *Fatigue *Abnormal thinking |
| What are Namenda, Cognex, and Aricept examples of ? | Alzheimer's Disease medications. |
| What is the mechanism of action of antidepressants? | *Exact mechanism is unknown. *Appear to increase neurotransmitters in the brain (Norepinephrine and Seratonin). *Usually take up to 3-6 weeks to take effect. |
| What are the side effects of antidepressants? | *Sedation *Anticholinergic (blocks neurotransmitters in the CNS) *Arrythmias *Seizures |
| What are Amitriptyline (Elavil), Desipramine (Norpramin), and Imipramine (Iofranil) examples of? | Tricyclic antidepressants |
| What are Fluoxetine (Prozac), Paroxetine (Paxile), Sertraline (Zoloft), and Escitalopram (Lexapro) examples of? | Serotonin and Norepinephrine reuptake inhibitors (used for depression). |
| What are Bupropion (Wellbutrin) and Lithium (Lithobid) used for? | Depression. |
| What are antipsychotics used for? | *Relieves signs and symptoms of psychosis *Have better effects on positive symptoms of psychosis *Auditory and visual hallucinations, agitation, suspicion, persecuting feelings, ideas of reference, and intrusion of unwanted thoughts. |
| What is the mechanism of action of antipsychotics? | *Originally proposed to block dopamine receptors in the brain. *Chemical effects unkown |
| What are the common side effects of antipsychotics? | *Sedation *Extrapyramidal symptoms (abnormal body movements) *Anticholinergic symptoms *Orthostatic hypotension *Arrythmias |
| What are Haldol, Thorazine, Compazine, Prolixin, Mallaril, Navane, and Stelazine examples of? | Typical antipsychotics |
| What are Clozaril, Risperdal, Zyprexa, Abilify, and Seroquel examples of? | Atypical antipsychotics |
| What are narcotic analgesics used for? | *Relief of moderate to severe pain *Cough suppressant (Antitussives) *Often combined with expectorants to help the patient cough up phlegm *Severe diarrhea |
| What is the mechanism of action of narcotic analgesics? | Bind to specific receptors within the brain and depress certain parts of the CNS to cause pain relief, respiratory depression, decreased GI motility, and suppression of cough. |
| What are common side effects of narcotic analgesics? | *Drowsiness *Consitipation *Nausea/vomiting *Addiction, tolerance and physical and psychological dependence *Overdoses can cause respiratory depression, profound coma, and pinpoint pupils (narcotic antagoniststreat overdoses- Naloxone or Narcan) |
| What are Codeine, Morphine Sulfate, Oxycodone, Hydromorphone (Dilaudid), Butorphanol (Stadol), Nalbuphine (Numbain), Meperidine (Demeral), Fentanyl (Duragesic) and Pentazocine (Talwin) examples of? | Single product narcotic analgesics. |
| What are Acetaminophen with codeine (tylenol with codeine), Hydrocodone and acetaminophen (Lorcet, Lortab, Vicodin), Oxycodone and Acetaminophen (Percocet, Roxicet) and Oxycodone and aspirin (Percodan) examples of? | Combination product narcotic analgesics. |
| What is Naloxone? | Opiod antagonist used to treat addiction such as oxycodone and heroine; Displaces opiod at opioid receptor sites. |
| What is Buprenophrine? | Exerts analgesic effect via high affinity binding to opiate receptors inthe CNS; Displays partial agonist and weak kappa antagonist activity. |
| What are anticonvulsants used for? | *Epilepsy-seizures accompanied by loss or disturbance of consciousness and possibly abnormal body movements (Convulsions). *Needs to be individualized by dose and addiction of other anticonvulsant agents. *Prevent the accurance of Seizures; don't cure |
| What is the mechanism of action of anticonvulsants? | Control the excessive discharge of signals from the brain (seizures) |
| What are side effects of anticonvulsants? | *Drowsiness *Slurred speech *Addiction *Tolerance and depencence *Respiratory and cardia depression (high doses) |
| What are Phenobarbital, Phenytoin (Dilantin), Fosphenytoin (Cerebyx), Carbamazepine (Tegretal),and Calproic acides and its derivatives (Depakene and depakote) | Anticonvulsants |
| What are skeletal muscle relaxants used for? | *Relieve muscle spasms associated with muscle inflammation and injury *Useful in neuromuscular disorders such as multiple sclerosis and cerebral palsy |
| What is the mechanism of action of skeletal muscle relaxants? | Not understood; may block nerve response within the spinal column; this has an effect of reducing muscle tone and relieveing spasms and tensions |
| What are the common side effects of skeletal muscle relaxants? | *Drowsiness *Addiction *Tolerance and dependence *Respiratory and cardiac depression (with high dose) |
| What are Diazepam (Valium), Cyclobenzaprine (Flexeril), Methocarbamul (Roboxin), Baclofen (Lioresal), Chlorzoxazon (Parafon forte), Carisoprodol (Soma), Metazolone (Skelaxin), Tizanidine (Zanaflex), and Orphenadrine (Norflex) examples of? | Skeletal muscle relaxants |
| What are Sedative Hypnotics used for? | *Short-term for insomnia *Long-term can cause drug-induced abnormalities in sleep cycle *Antidotes for overdoses of stimulants *In combonation with analgesics in painful situations *Preoperative anesthitics |
| What is the mechanism of action of Sedative hypnotics? | Not certian; believed to reduce activity of brain and spinal cord |
| What are side effects of sedative hypnotics? | *Drowsiness *Addiction *Tolerance and dependence *Respiratory and cardiac depression (high doses) |
| What are Flurazepam (Dalmane), Alprazolam (Xanax), Lorazepam (Ativan), Diazepam (Valium), Oxazepam (Serax), Midazolam (Versed), Temazepam (Restoril), Triazolam (Halicon), Estazolam (ProSam), Clonazepam (Klonopin), and Quazepam (Doral) exapmles of? | Benzodiazepine Sedative hypnotics |
| What are Secobarbital (Seconal), Amobarbital (Anytal), Phenobarbital (Nembutal), and Butabarbital (Butisol) examples of? | Sedative Hypnotics |
| How to tell if some drugs are benzodiazepines? | Most end in "-pam" or "-lam" |
| What are Zolpidem (Ambien), Eszopiclone (Lunesta), Zaleplon (Sonata), and Ramelton (Rozerem) examples of? | Nonbenzodiazepines used for insomnia |
| What are Diphenhydramine (benadryl, compoz, nytol, and sominex) examples of? | Antihistamines |
Created by:
Martinafulgieri
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