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interactions 2

Cyp inducers/inhibitors

QuestionAnswer
St. Johns Wart Induce 3A4
Pioglitazone Induce 3A4
Phenytoin Induce 3A4
Phenobarbital Induce 3A4
Substrates of CYP 2d6 codeine, duloxetine, BBs, flecainide, TCAs, ondasetron, haloperidol, tamoxifen, resperidone, tramadol, thiodazone, venalafaxine
Fluxetine Inhibit - 2D6
Haloperidol Inhibit CYP 2D6
Bupropion Inhibit CYP 2D6
Paroxetine Inhibit CYP 2D6
Quinidine Inhibit CYP 2D6
Duloxetine Inhibit CYP 2D6
Amiodarone Inhibit CYP 2D6
Goldenseal Inhibit CYP 2D6
Substrates of 2C19 diazepam, rabeprazole, phenytoin, amitriptyline, omeprazole, clomipramine, lazoprazole, cyclophosphamide, pantoprazole, progesterone, clopidogrel
Omeprazole/Lansoprazole Inhibit 2C19
Fluoxetine Inhibit 2C19
Fluoxamine Inhibit 2C19
Isoniazid Inhibit 2C19, 2C9
CYP 2C9 substrates of NSAIDS + COX 2, Irbesartan, Warfarin, Fluvastatin, Phenytoin, Rosiglitazone, Tolbutamide, Sulfamethaxazole,Glipizide, Tamoxifen, Losartan, Torsemide
Amiodarone Inhibit 2C9
Voriconazole Inhibit 2C9
Created by: sweetgecko
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