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antivirals hiv
name, brand generic, important facts
| Question | Answer |
|---|---|
| Zidovudine | Retrovir - NRTI - Macrocystosis |
| Lamivudine | Epivir - NRTI - Renal dosed - used in Hep B too |
| Stavudine | Zerit - NRTI - Peripheral Neuropathy - avoid use with Zidovudine |
| Didanosine | Videx - NRTI - Pancreatitis, Peripheral Neuropathy - buffered tabs have Ca, Mg watch with Fqs and tetracyclines |
| Abacavir | Ziagen - NRTI - hypersensativity - genetic testing required - no renal dosing needed |
| Emtricitabine | Emtriva - NRTI - |
| Zalcitabine | Hivid - NRTI - P. Neuropathy, |
| Lamuvidine/Zidovudine | Combivir |
| Abacavir/Lamivudine/Zidovudine | Trizivir |
| Abacavir/Lamivudine | Epzicom |
| Efavirenz/Emtricitabine/TNF | Atripla |
| Tenofovir | Viread - nucleotide RTI - renal tox/failure, prodrug - 2 phos needed |
| Tenofovir/emtricitabine | Truvada |
| Efavirenz | Sustiva - NNRTI - avoid with fatty meals, psycosis, Pregnancy D, false + marijuana and urine tox |
| Delavirdine | Rescriptor - NNRTI - antacids affect metabolism |
| Nevirapine | Viramune - NNRTI - autoinducer, hepatoxicity (first 4 weeks) |
| Etravirine | Intelence - NNRTI - only in resistance cases - avoid with unboosted PI |
| Saquinavir | Fortovase, Invirase , PI, take with fatty food, take with RIT, X rifampin |
| Indinavir | Crixivan - PI - increase bili, antacids, drink alot |
| Nelfinavir | Viracept - PI - powder |
| Ritonavir | Norvir - PI - used in combo, inhibits the meta. of other PIs |
| Fosamprenavir | Lexiva - PI - prodrug amprenavir - |
| Lopinavir/RTV | Kaletra - PI - |
| Atazanavir | Reyataz - PI - hyperbili, (used to check compliance), dose limited ppi's, |
| Tipranavir | Aptivus - PI - |
| Darunavir | Prezista - PI - |
| Enfuviratide | Fuzeon - PI - added onto others |
| Maraviroc | Selzentry - PI - |
| Raltegravir | Isentress - PI - |