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Exam- 2
antiparasitic,antifunal
| Major/Sub Class | Generic/Trade | Adverse affects | How it works |
|---|---|---|---|
| antiprotozoal/ antimalarial | chloroquine/Aralen | N D, GI upset, Caution with G6PD,antiacids, laxitive, CNS and CV toxic | weakens cell membrane |
| antiparasitic/ no sub | metronidazole/Flagyl | N D, HA, dizzy, anorexic, GI upset, dry mouth, metallic taste, Caution with alcohol and anticoagulants, Urine turns red | disrupts DNA |
| antiparasitic/ antihelminthic | mebendazole/Vermox | distention, diarrhea, abdomen pain | prevents uptake of glucose by worms |
| antifungal/no sub | amphotericin-B /Fungizone | fever, chills, Vomit, HA at onset, Hypotension, nephrotoxic, electrolyte imbalance, dysrhythmia, cardia arrest, phlebitis | cell membrane becomes permeable (leaky) |
| antifungal/no sub | fluconazole/Diflucan | N V D, HA rash, abdomen pain, use caution in Renal | interferes with fungi reproduction |
| antifungal/no sub | nystatin/Mycostatin | PO-GI upset Topical-Skin irritate swish and swallow | weakens cell membrane |