Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


HMG- CoA reductase Inhibitor

HGM- CoA reductase inhibitors ("statins") Lipitor (atorvastatin ) Zocor ( simvastatin)
Mechanism of Action 1. Inhibit the HMG- CoA reductase enzyme activity in the liver 2. Decreases cholesterol synthesis
Therapeutic effect 1. Decreases total collateral 2. May affect individual types of cholesterol •HDL, LDL etc.
Precautions 1. Hyperglycemia 2. Pre-existing muscle weakness 3. Altered neuro status; pre-existing confusion/dementia 4. Liver dysfunction (elevated liver function test LTSs)
Contraindications 1. Pregnancy category x 2. Liver dysfunction 3. Renal insufficiency/ failure due to rhabdomyolysis, trauma
Side Effects 1. Hyperglycemia 2. Myopathy (muscle weakness) rhabdomyolysis (breakdown of skeletal muscle that travels to kidney for excretion)! 3. Headache, memory loss, confusion 4. Gastrointestinal (GI) disturbances, liver dysfunction
Nursing Actions 1. Optimal dosing time: nocturnal 2. Assess: neuro function, muscle weakness, glucose control, GI symptoms, Urinary changes 3. Drug interactions (CYP 450)! 4. Follow lipid Panel; monitor glucose and LFTs
Created by: azmedina



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards