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CNS Drugs
These drugs affect the Central Nervous System
Drug Name | Trade Name | Drug Classification | Used to Treat | Controlled Drug Status |
---|---|---|---|---|
Acepromazine melate | PromAce | Phenothiazine Derivative | Tranquilizer - sedation and allay fear and anxiety | N/A |
Chlorpromazine hydrochloride | Thorazine (human label) | Phenothiazine Derivative | Tranquilizer - sedation and allay fear and anxiety | N/A |
Promazine HCl | Sparine (human label) | Phenothiazine Derivative | Tranquilizer - sedation and allay fear and anxiety | N/A |
Prochlorperazine | Compazine (human label) | Phenothiazine Derivative | Tranquilizer - sedation and allay fear and anxiety | N/A |
Diazepam | Valium, Diastat | Benzodiazepine Derivative | Tranquilizer - sedation, muscle relaxation, appetite stimulation (in cats), and anticonvulsant activity | N/A |
Midazolam | Versed | Benzodiazepine Derivative | Tranquilizer - sedation, muscle relaxation, appetite stimulation (in cats), and anticonvulsant activity | N/A |
Alprazolam | Xanax | Benzodiazepine Derivative | Tranquilizer - sedation, muscle relaxation, appetite stimulation (in cats), and anticonvulsant activity | N/A |
Rompun | N/A | Xylazine Hydrochloride | Tranquilizer - sedative, analgesic, and muscle relaxant properties | N/A |
AnaSed | N/A | Xylazine Hydrochloride | Tranquilizer - sedative, analgesic, and muscle relaxant properties | N/A |
Gemini | N/A | Xylazine Hydrochloride | Tranquilizer - sedative, analgesic, and muscle relaxant properties | N/A |
Sedazine | N/A | Xylazine Hydrochloride | Tranquilizer - sedative, analgesic, and muscle relaxant properties | N/A |
Cervizine | N/A | Xylazine Hydrochloride | Tranquilizer - sedative, analgesic, and muscle relaxant properties | N/A |
Dromosedan injectable | N/A | Detomidine Hydrochloride | Tranquilizer - sedation and analgesia in horses | N/A |
Dormosedan Gel | N/A | Detomidine Hydrochloride | Tranquilizer - sedation and analgesia in horses | N/A |
Domitor | N/A | Medetomidine | Tranquilizer - Sedative and analgesic in dogs (older than 12 wks) | N/A |
Dexdomitor | N/A | Dexmedtomidine | Tranquilizer - sedative and analgesic in dogs and cats | N/A |
Sedivet | N/A | Romifidine | Tranquilizer - alpha-2-andrenergic agonist labeled for use in horses | N/A |
Phenobarbital | Luminal | Long-Acting Oxybarbiturate | Anticonvulsant to prevent epileptic seizures | Class IV |
Pentobarbital sodium | Nembutal | Short-Acting Oxybarbiturate | 1-2 hrs of general anesthesia | Class II |
Thiopental | Pentothal | Ultrashort-Acting Oxybarbiturate | Anesthetic | N/A |
Ketamine HCl | Ketaset, Vetalar, Ketalar | Dissociative Agent | Enhance muscle relaxation and deepen the level of anesthesia | Class III |
Tiletamine HCl | Telazol | Dissociative Agent | Enhance muscle relaxation and deepen the level of anesthesia | Class III |
Phencyclidine (street names "PCP" or "angel dust") | Sernylan | Dissociative Agent | Immobilizing agent for nonhuman primates | **NO LONGER AVAILABLE** |
Opium | N/A | Naturally Occurring Narcotic | Diarrhea | N/A |
Morphine sulfate | Duramorph | Naturally Occurring Narcotic | Severe pain; occasionally used as a preanesthetic or anesthetic agent (e.g. c-section in dog); relieve anxiety associated with acute congestive heart failure | Class II |
Meperidine | Demerol | Synthetic Narcotic | Relief of acute pain; combined with tranquilizer for use as an anesthetic agent | N/A |
Oxymorphone | Numorphan, Opana | Synthetic Narcotic | In dogs as chemical restraint, diagnostic procedures, minor surgical procedures; combined with tranquilizer to produce neuroleptanalgesia | N/A |
Butorphanol tartrate | Torbutrol, Torbugesic | Synthetic Narcotic | Antitussive agent in dogs; preanesthetic or for minor surgical procedures in cats and dogs | Class IV |
Fentanyl | Recuvrya, Sublimaze, Duragesic (human labels) | Synthetic Narcotic | Control chronic pain | Class II |
Hydrocodone bitartrate | Hycodan, Tussigon | Synthetic Narcotic | Antitussive in dogs | Class III |
Etorphine | M-99 | Synthetic Narcotic | Restricted to use by veterinarians in zoo or exotic animal practices | Class II |
Pentazocine | Talwin | Synthetic Narcotic | Pain relief in horses and dogs | Class IV |
Diphenoxylate | Lomotil | Synthetic Narcotic | Combined with atropine for use as an antidiarrheal agent | Class V |
Apomorphine | Apokyn (human label and generic products) | Synthetic Narcotic | Inducing vomiting | N/A |
Methadone | Dolophine | Synthetic Narcotic | Treatment of colic pain in horses | Class II |
Codeine | N/A | Synthetic Narcotic | Antitussive in dogs | Class II when used alone Class III or Class V when used in combination products |
Carfentanil | Wildnil | Synthetic Narcotic | Induce wildlife anesthesia | Class II |
Buprenorphine | Buprenex | Synthetic Narcotic | Potent analgesic | N/A |
Tramadol | N/A | Synthetic Narcotic | Alternative analgesic agent or as an adjunct for postoperative or chronic pain in dogs and horses | N/A |
Naloxone | Naloxone HCl injection, Narcan | Opioid Antagonist | Pure opioid antagonist | N/A |
Nalorphine | Nalline | Opioid Antagonist | Partial antagonist | N/A |
Butorphanol-mu | N/A | Opioid Antagonist | Sedative or analgesic | N/A |
Fentanyl and droperidol | Innovar-Vet | Neuroleptanalgesic | Sedation, restraint, anesthesia | N/A |
Acepromazine and morphine | N/A | Neuroleptanalgesic | Sedation, restraint, anesthesia | N/A |
Acepromazine and oxymorphone | N/A | Neuroleptanalgesic | Sedation, restraint, anesthesia | N/A |
Xylazine and butorphanol | N/A | Neuroleptanalgesic | Sedation, restraint, anesthesia | N/A |
Diazepam | Valium | Drug Given to Prevent Or Control Seizures | Tranquilizer with potent antiseizure properties | N/A |
Pentobarbital | Nembutal and generic products | Drug Given to Prevent Or Control Seizures | Short-acting barbiturate that is effective for controlling seizures | N/A |
Phenobarbital | Luminal, Solfoton, generic formulations | Drug Given to Prevent Or Control Seizures | Antiseizure | Class IV |
Primidone | Mysoline (human label), Neurosyn (veterinary) | Drug Given to Prevent Or Control Seizures | Antiseizure | N/A |
Phenytoin sodium | Dilantin | Drug Given to Prevent Or Control Seizures | Occasionally used in combination with other antiseizure meds | N/A |
Bromide | N/A | Drug Given to Prevent Or Control Seizures | Anticonvulsant | N/A |
Clorazepate | Tranxene-SD | Drug Given to Prevent Or Control Seizures | Used as an adjunctive with other antiseizure agents | N/A |
Felbamate | Felbatol | Drug Given to Prevent Or Control Seizures | Used for complex or partial seizures | N/A |
Gabapentin | Neurontin | Drug Given to Prevent Or Control Seizures | Adjunctive treatment of seizures that are difficult to control, as well as for partial complex seizures or pain control | N/A |
Levetiracetam | Keppra | Drug Given to Prevent Or Control Seizures | Adjunct for refractory canine epilepsy | N/A |
Zonisamide | Zonegran | Drug Given to Prevent Or Control Seizures | Adjunct for refractory canine epilepsy | N/A |
Isoflurane | Forane (human label), IsoFlo (veterinary), Isothesia (veterinary) | Inhalant Anesthetic | Rapid induction and recovery times | N/A |
Sevoflurane | Ultane (human label), SevoFlo (veterinary) | Inhalant Anesthetic | Rapid induction and recovery times; used in high-risk, small-animal patients | N/A |
Halothane | Fluothane | Inhalant Anesthetic | Rapid induction and recovery times | N/A |
Methoxyflurane | Metofane | Inhalant Anesthetic | Very slow induction and recovery times | N/A |
Nitrous oxide | N/A | Inhalant Anesthetic | Used as an adjunct to more potent agents during mask induction to speed the induction of anesthesia | N/A |
Propofol | Rapinovet, PropoFlo, Diprivan (human label), PropoFlo-28, PropoClear | Miscellaneous CNS Drug | Useful for anesthetic induction before administration of an inhalant anesthetic, for outpatient procedures, subsitute for barbiturates in sighthounds, for patients with preexisting cardiac arrhythmia, anesthetic for dogs undergoing c-section | N/A |
Glyceryl Guaiacolate or Guaifenesin | Guailaxin, Gecolate, Guaifenesin Injection, GuaifenJect | Miscellaneous CNS Drug | Induction or prolongation of general anesthesia in large animals and occasional use as an expectorant | N/A |
Chloral Hydrate/Magnesium Sulfate | N/A | Miscellaneous CNS Drug | IV agent to produce anesthesia in large animals | *not commonly used |
Doxapram | Dopram-V, Dopram (approved for human use) | CNS Stimulant | Stimulate respiration in newborns and use during anesthesia | N/A |
Pentylenetetrazol | Metrazol | CNS Stimulant | Stimulate respirations and to hasten recovery from anesthesia; limited use in veterinary medicine | N/A |
Caffeine | N/A | CNS Stimulant | Promotes wakefulness | N/A |
Amphetamines | N/A | CNS Stimulant | Potent stimulant of the cerebral cortex | *few legitimate uses in veterinary medicine |
Succinylcholine chloride | Anectine (human label) | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Decamethonium | Syncurine | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
d-Tubocurarine chloride | Curare | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Gallamine | Flaxedil | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Pancuronium bromide | Pavulon | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Vecuronium bromide | Norcuron | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Atracurium | Tracrium | Neuromuscular Blocking Agent (Muscle Relaxant) | Adjunct to general anesthesia and to facilitate endotracheal intubation | N/A |
Diazepam | Valium | Antianxiety Medication (Benzodiazepines) | Fears and phobias, separation anxiety, aggression, anxiety-induced stereotypes, urine marking in cats, and appetite stimulation | N/A |
Alprazolam | Xanax | Antianxiety Medication (Benzodiazepines) | Fears and phobias, separation anxiety, aggression, anxiety-induced stereotypes, urine marking in cats, and appetite stimulation | N/A |
Lorazepam | Ativan | Antianxiety Medication (Benzodiazepines) | Fears and phobias, separation anxiety, aggression, anxiety-induced stereotypes, urine marking in cats, and appetite stimulation | N/A |
Buspirone | Buspar | Antianxiety Medication (Azapirones) | Control of urine spraying/marking, fearfulness, anxiety | N/A |
Amitriptyline | Elavil, generic forms | Antidepressant (Tricyclic) | Separation anxiety, obsessive disorders, fearful aggression, hyperactivity, hypervocalization, and urine marking | N/A |
Imipramine | Tofranil | Antidepressant (Tricyclic) | Separation anxiety, obsessive disorders, fearful aggression, hyperactivity, hypervocalization, and urine marking | N/A |
Clomipramine | Anafranil, Clomicalm | Antidepressant (Tricyclic) | Separation anxiety, obsessive disorders, fearful aggression, hyperactivity, hypervocalization, and urine marking | N/A |
Fluoxetine | Prozac (human label), Reconcile (dogs) | Antidepressant (Serotonin Reuptake Inhibitor) | Obsessive disorders, phobias, aggression, separation anxiety | N/A |
Sertraline | Zoloft | Antidepressant (Serotonin Reuptake Inhibitor) | Obsessive disorders, phobias, aggression, separation anxiety | N/A |
Paroxetine | Paxil | Antidepressant (Serotonin Reuptake Inhibitor) | Obsessive disorders, phobias, aggression, separation anxiety | N/A |
Fluvoxamine | Luvox | Antidepressant (Serotonin Reuptake Inhibitor) | Obsessive disorders, phobias, aggression, separation anxiety | N/A |
Selegiline | Eldepryl, Zelapar, Anipryl | Antidepressant (Monoamine Oxidase-B Inhibitor) | Old-dog dementia, canine Cushing's disease | N/A |
Megestrol acetate | Megace, Ovaban | Antidepressant (Synthetic Progestin) | Urine spraying/marking, intermale aggression, dominance aggression | N/A |
Medroxyprogesterone | Depo-Provera | Antidepressant (Synthetic Progestin | Urine spraying/marking, intermale aggression, dominance aggression | N/A |
Gabapentin | N/A | Miscellaneous Behavioral Agent | Anxiety or social phobia | N/A |
Clorazepate | Tranxene-SD | Miscellaneous Behavioral Agent | Anxiety or social phobia | Class IV |
Methylphenidate | Ritalin | Miscellaneous Behavioral Agent | Hyperactivity in dogs | Class II |
Pentobarbital sodium | Sleepaway, Socumb-6GR, Fatal Plus, pentobarbital generic | Euthanasia Agent | Used for euthanasia | Class II |
Pentobarbital sodium | Beuthanasia, Euthasol, SomnaSol | Euthanasia Agent | Used for euthanasia *different from other: contains rhodamine B (bluish-red dye), phenytoin, preservative | Class III |