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PHAT 162 week 1
| Question | Answer |
|---|---|
| Male Reproductive Structures | Testes, epididymis, Vas Deferens, seminial vesicles, prostate gland, bulbourethral (cowper's) gland, scrotum, and penis |
| Female Reproductive Strucuture | ovaries, uterine (fallopian) tubes, uterus, vagina |
| Male sex cells | sperm |
| Female sex cells | Oocytes (eggs) |
| Male sex hormones are called | androgens |
| Most abundant male sex hormone | testosterone |
| Female sex hormones are | estrogens and progestrogens |
| Most abundant female sex hormone is | estradiol |
| Puberty | the age when an individual becomes reproductively functioning |
| The chief drugs that afeect the male reproductive system are | androgens and anabolic steroids |
| HRT | hormone replacement therapy |
| BCP | birth control pills ( oral contraceptive) |
| GnRH | Gonadotropin Releasing hormone |
| FSH | follicle stimulating hormone |
| LH | lutenizing hormone |
| Most common from of contraception in the U.S is | oral contraceptives |
| Oral contraceptives | usually consist of combinations of estrogen and progestrone derivatives to prevent pregnancy |
| Oral contraceptives are available that contain progesterone(progestin) only. these are also known as | POPS "Progestin Only Pills" |
| POPS have a silghtly higher failure rate than the combination BCP's. Example of POP | Mironor(norethindrone) |
| Oral contraceptives should be discontinued at least $ weeks prior to | surgical porcedures to reduce the risk of post operative thromboembolic complications |
| Pregnancy usually continues | for 38 weeks after conception |
| Post menopausal patients | are on long term estrogen therapy and should also be given progestin to prevent endometrial hyperplasia and endometrial carcinoma |
| Progestin | SHOULD NOT be given to women who have had a hysterectomy |
| Androgens therapy | Main indications |
| Main indications in Men | to supplement low levels of testosterone to correct hypogonadism or cryptorchidism to increase sperm production in cases of infertility |
| Main indications in women | Palliative treatment of metastatic breast cancer, for treatment of postpartum breast engorgement, endometriosis, and fibrcystic breast disorder |
| The use of testosterone during pregnancy | can cause masculinization of the fetus, particularly if testoseterone (androgen) therapy is used during th e1st trimester |
| Androgen therapy | is also used to stimulate increased production of RBC's protein synthesis and muscle mass |
| Atheletes | may use androgens to improve athletic performance. "This is Illegal" |
| Estrogen therapy | estrogen therapyq |
| Estrogens | are used in both genders, includuing replacement estrogen therapy in women who have had their ovaries removed during their reporductive years. In older women for the prevention and treatment of osteoporosis, and as a palliative therapy for breast and pros |
| Estrogen therapy | is contraindicated in women with breast cancer, pregnancy, and lactation |
| MOA | Mechanism of Action |
| PPI | Patient Package Insert |
| The Renal System | Urinary |
| The structures and functions of the urinary system | 2 kidneys,2 ureters, 1 urinary bladder, and 1 urethra |
| 2 Kidneys | produce and regulate body fluids |
| 2 Ureters | transport urine to the urinary bladder |
| 1Urinary bladder | serves as a reservoir for urine |
| 1 Urethra | conveys urine form the urinary bladder to the outside of the body |
| 5 major calsses of diuretics | osmotic diuretics, carbonic anhydrase inhibitors, thiazide and thiazide like diuretics, loop diuretics and potassium sparing diuretcis |
| osmotic diuretics | ex. Mannitol. Mannitol is currently the ONLY osmotic diuretic on the market. Osmitrol (Mannitol) |
| Carbonic Anhydrase diuretics | Ex. Diamax(acetazoleamide), neptazone(methazolamide) |
| Thiazide and thiazide like diuretics | ex. Oretic (hydrochlorothizide) HCTZ, and Diurel (chlorothiazide) |
| Loop Diuretics | ex. Bumex (bumetanide) and lasix (furosemide) |
| Potassium sparing diuretics | ex. Aldactone(spironolactone) and Midamor(amiloride) |
| Osmotic diuretics | are highly effective in the treatment of cerebral edema and are primarily used for this purpose. Must be kept in warm oven or a t room temp @86 degrees F- 98 degrees F |
| Carbonic Anhydrase Inhibitors | are used to treat glaucoma and epilepsy and to lessen the effects of high altitudes on the body |
| Thiazide and thiazide like diuretics | are mainly osed in the treatment of HTN |
| Loop Diuretics | are commonly referred to as "high ceiling diuretics". In high doses loop diuretics can increase urine output astrnomically, leading to severe hypovolemia and death. They are the drugs of choice(DOC) in the treatment of pulmonary edema |
| Loop diuretics | are used in the treatment of HTN when other diuretics and antihypertensive DO NOT produce a satisfactory response |
| Potassium sparind diuretics | are used in the treatment of edema associated with CHF, cirrhosis of the liver and kidney disease |
| Hypovolemia | low volume of blood |
| UTI | urinary tract infection |
| BPH | Benign Prostatic Hyerpasia |
| Hyperplasia | is an abnormal enlargement of the prostate gland. This is the most common medical condition occuring in older men. primarily treated with alpha blockers ex. Uroxatrol(alfuzosin) |
| nocturia | frequent urination at night |
| stress incontinence | urine leakage during physical movement |