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3rd Top 200b

3rd Top 200

ClassBrand(s)GenericIndication & DosingC/IADRsBBW
Analgesic, Opioid Dolophine (C-II) methadone (Y) Chronic pain: q8-12h Detoxification: once IV soln, oral soln, tab Resp depression, Asthma, Hypercarbia, Paralytic ileus, Selegiline None **Addiction, abuse, & misuse* *Life-threatening resp. depression* *Life-threatening QT prolongation* *Accidental exposure* *Neonatal opioid w/drawal* *Tx of opioid addiction* *Appropriate use* *Cardiac conduction effects**
Analgesic, Opioid OxyContin, Roxicodone (C-II) oxycodone (Y) Pain: q4-6h PRN (IR) or q12h (ER) cap, oral conc, oral soln, tab, ER tab Resp depression, Hypercarbia, Asthma, Paralytic ileus, GI obstruction Drowsiness Pruritus Constipation Fever **Addiction, abuse, & misuse* *Life-threatening resp. depression* *Accidental ingestion* *Neonatal opioid w/drawal* *CYP3A4 interaction* *Appropriate use (oral concentration & solution)**
Analgesic, Opioid ConZip, Ultram, Ultram ER, Ryzolt, Rybix (C-IV) tramadol (?) Pain: q4-6h (IR) or daily (ER) ER cap, ER tab, ODT, tab Resp depression, Asthma, GI obstruction, Paralytic ileus, MAOI Flushing CNS stimulation Xerostomia Weakness **Addiction, abuse, & misuse* *Life-threatening resp. depression* *Accidental ingestion* *Neonatal opioid w/drawal* *CYP P450 interaction* *Risks from concomitant use w/ benzos or other CNS depressants**
Analgesic, Opioid Combination Percocet (C-II) oxycodone/APAP (Y) Pain: q6h PRN tab Resp depression, Asthma, Hypercarbia, Paralytic ileus DZ Nausea **Addiction, abuse, & misuse* *Life-threatening resp. depression* *Accidental exposure* Neonatal opioid w/drawal* *CYP3A4 interaction* *Hepatotoxicity* *Concomitant use w/ benzos or other CNS depressants**
Antibiotic, Penicillin Amoxil, Trimox, Moxatag (Rx) amoxicillin (Y) ENT inf, GU inf, H. pylori, RTI, pharyngitis & tonsillitis, SASSI: q8-12h (IR) or daily (ER) cap, susp, tab, chew tab, ER tab None None None
Antibiotic, Penicillin Augmentin (Rx) amoxicillin/clavulanic acid (Y) CAP, otitis, RTI, sinusitis, SASSI, UTI susp, tab, chew tab, tab ER Hx of hepatic dysfx w/med, Renal dysfx Diarrhea None
Antibiotic, Penicillin Penicillin G, Penicillin VK (Rx) penicillin G, penicillin VK (Y) Gram (+) inf, etc: q6-8h IM & IV soln (G), oral soln & tab (VK) None (VK) Melanoglossia, oral candidiasis None
Anticholinergic Agent Bentyl (Rx) dicyclomine (Y) IBS: QID cap, IM soln, oral soln, tab Obstruction in GI/uropathy, Ulcerative colitis, Esophagitis, Unstable CV (in acute hemorrhage), Glaucoma, Myasthenia gravis, Breastfeeding, < 6M DZ Xerostomia Blurred vision None
Anticonvulsant Topamax (Rx) topiramate (Y) Epilepsy: BID, Migraine Px: QPM cap sprinkle, tab None Patesthesia, memory impairment Weight loss Anorexia Upper RTI Fever None
Anticonvulsant; GABA Analog Neurontin, Horizant, Gralise (Rx) gabapentin (?) PHN:QAM-BID, RLS: QPM, Seizures: TID cap, oral soln, tab, tab ER None DZ, ataxia viral inf None
Antidepressant, SNRI Cymbalta (Rx) duloxetine (Y) Chronic pain, DPN, Fibromyalgia, GAD, MDD: daily cap DR MAOI, Linezolid, IV methylene blue HA Xerostomia Weight loss Weakness **Suicidal thoughts & behavior**
Antidepressant, TCA (Secondary Amine) Pamelor (Rx) nortiptyline (Y) Depression: TID-QID cap, oral soln Dibenazaepine allergy, Acute MI, MAOI, Linezolid, IV methylene blue None **Suicidality in children & adolescents**
Antidepressant, TCA, Alpha2 Antagonist Remeron (Rx) mirtazepine (Y) MDD: QPM ODT, tab MAOI, Linezolid, IV methylene blue Drowsiness Weight gain Xerostomia **Suicidality & antidepressant drugs**
Antidiabetic Agent, Biguanide Glucophage, Riomet, Fortamet (Rx) metformin (?) T2DM: daily-BID oral soln, tab, tab ER Renal dysfx, Metabolic acidosis Diarrhea, flatulence **Lactic acidosis**
Antidiabetic Agent, Biguanide & DPP-4 Inhibitor Janumet (Rx) sitagliptin/metformin (N) T2DM: daily-BID tab, tab ER Renal dysfx, Metabolic acidosis None **Lactic acidosis**
Antidiabetic Agent, DPP-4 Inhibitor Onglyza (Rx) saxagliptin (N) T2DM: daily tab None None None
Antidiabetic Agent, DPP-4 Inhibitor Januvia (Rx) sitagliptin (N) T2DM: daily tab None None None
Antidiabetic Agent, GLP-1 Receptor Agonist Byetta, Bydureon (Rx) exenatide (N) T2DM: BID (IR) or weekly (ER) SQ pen Cancers (thyroid, endocrine) Ha Hypoglycemia Injection site nodule/rxn **Risk of thyroid C-cell tumors (Bydureon)**
Antidiabetic Agent, GLP-1 Receptor Agonist Victoza, Saxenda (Rx) liraglutide (N) Chronic weight mgt, T2DM: daily SQ pen Cancers (thyroid, endocrine) Pregnancy (Sax) Inc HR HA Hypoglycemia N/V/D/C **Thyroid C-cell tumor risk**
Antidiabetic Agent, Thiazolidinedione Actos (Rx) pioglitazone (Y) T2DM: daily tab HF Edema Hypoglycemia Upper RTI **CHF**
Antiemetic, Histamine H1 Antagonist Phenergan (Rx) promethazine (Y) Allergy: HS +/- AC, N/V: q4-6h PRN, Motion sickness: BID, Surgical analgesia, etc, Sedation: once IM/IV soln, supp, oral soln, syrup, tab Coma, lower RTI, age < 2, Intra-arterial/SQ admin None **Resp. depression (peds)* *Severe tissue injury, including gangrene (injection)**
Antiemetic, Selective 5-HT3 Receptor Antagonist Zofran (Rx) ondansetron (?) CINV, RANV, Px PONV: prior +/- q4 (IV), 8-12 (PO)h inj soln, ODT, soln, tab Apomorphine HA Constipation None
Antimigraine Agent, 5-HT1B, 1D Agonist Imitrex (Rx) sumatriptan (Y) Migraine, Cluster HA: once, may repeat in 2h PRN nasal soln, SQ soln, tab Ischemic heart disease, cerebrovascular syn, PVD, HTN, ergots, MAOIs, arrhythmias, hepatic dysfx (inj) Tingling, injection site rxn (nasal) dysgeusia None
Antiretroviral, Protease Inhibitor (Anti-HIV) Prezista (Rx) darunavir (N) HIV: daily-BID w/ritonavir susp, tab CYP3A4s w/NTI Rash Hypercholesterolemia, hyperglycemia N/V/D None
Antiretroviral, Reverse Transcriptase Inhibitor, (Anti-HIV) Atripla (Rx) emtricitabine/tenofovir/efavirenz (N) HIV: daily tab Bepridil, cisapride, midazolam, triazolam, vori, ergots, St John's, pimozide Hypercholesterolemia **Lactic acidosis/severe hepatomegaly w/steatosis* *Hep B coinfection**
Antiviral Agent Zovirax (Rx) acyclovir (Y) HSV, HZV, Varicella: BID-FID cap, IV soln, susp, tab None Malaise None
CNS Stimulant Aptensio XR, Concerta, Daytrana, Ritalin, Metadate, Methylin (C-II) methylphenidate (?) ADHD, Narcolepsy: QAM-BID cap ER, patch, oral soln, tab, chew tab, tab ER MAOI, Anxiety, Glaucoma, Tourette syn (more for cap ER like halogenated anesthetics & fructose intolerance) HA Decreased appetite **Abuse & dependence**
Histamine H2 Antagonist Pepcid (Rx) famotidine (Y) Ulcers, GERD, etc: QHS-BID, Hypersecretory cond: q6h IV soln, susp, tab None Agitation Vomiting None
Histamine H2 Antagonist Zantac (Rx [OTC]) ranitidine (?) Ulcers, GERD, etc., Hypersecretory cond: QPM-QID or cont IV cap, IM soln, IV soln, syrup, tab None None None
Hypnotic Ambien, Ambien CR, Edluar, Zolpimist, Intermezzo (C-IV) zolpidem (?) Insomnia: QHS oral inh, tab, tab ER, SL tab None HA None
Insulin, Intermediate-Acting Humulin N, Humulin R (Rx [OTC]) insulin (N) DM: varies SQ soln, SQ pen Hypoglycemia None None
Insulin, Long-Acting Levemir (Rx) insulin detemir (N) DM: QPM-BID SQ soln, SQ pen None HA Hypogylcemia Gastroenteritis Flu-like Sx None
Insulin, Long-Acting Lantus, Lantus Solostar (Rx) insulin glargine (N) DM: daily SQ soln, SQ pen Hypoglycemia HTN Depression Hypoglycemia Diarrhea UTI Infection Arthralgia Retinopathy Sinusitis None
Insulin, Rapid-Acting NovoLog, NovoLog Flexpen (Rx) insulin aspart (N) DM: daily SQ soln, SQ pen Hypoglycemia Hypoglycemia HA Accidental injury None
Insulin, Rapid-Acting Humalog, Humalog Kwikpen (Rx) insulin lispro (N) DM: daily SQ soln, SQ pen Hypoglycemia HA Infection Flu-like Sx None
N-Methyl-D-Aspartate Receptor Antagonist Namenda, Namenda XR (Rx) memantine (?) AD: daily-BID cap ER, oral soln, tab None None None
NSAID, Oral; Analgesic, Nonopioid Mobic (Rx) meloxicam (?) OA, RA: daily tab Asthma, allergy-type rxn from ASA/NSAIDs, CABG surgery None **Serious CV thrombotic events* *Serious GI bleeding, ulcerations, & perforation**
PPI, Substituted Benzimidazole Nexium (Rx) esomeprazole (?) EE, GERD, H. pylori, Px NSAID-induced ulcer: daily, Px of ulcer bleeding: bolus & cont IV, Hypersecretory cond: BID cap DR, packet, IV soln, tab DR None HA None
PPI, Substituted Benzimidazole Prevacid (Rx [OTC]) lansoprazole (?) GERD, EE, NSAID-associated ulcer, Hypersecretory cond, PUD: daily-BID, H. pylori: BID-TID cap DR, ODT None None None
PPI, Substituted Benzimidazole Prilosec (Rx [OTC]) omeprazole (?) Ulcer, GERD, EE, H. pylori: daily-BID, Hypersecretory cond: daily-TID cap DR, packet, tab DR Rilpivirine None None
PPI, Substituted Benzimidazole Protonix (Rx) pantoprazole (?) EE: daily, Hypersecretory cond: BID packet, IV soln, tab DR None HA None
PPI, Substituted Benzimidazole Aciphex (Rx) rabeprazole (?) Ulcer, GERD, H. pylori, Hypersecretory cond: daily-BID cap sprinkle, tab DR Rilpivirine None None
SGA; Antimanic Agent Zyprexa (Rx) olanzapine (?) Schizophrenia, Bipolar & associated Depression: QPM, Agitation: once, may repeat in 2hr, then 4hr IM soln, ODT, tab None Orthostatic hypotension EPS Weight gain Dyspepsia Weakness Accidental injury **Increased mortality in elderly pts w/dementia-related psychosis**
Thyroid Product Synthroid, Levoxyl, Levothroid [DSC], Unithroid, Tirosint (Rx) levothyroxine (?) Hypothyroidism, TSH suppression, Myxedema: daily cap, IV soln, tab Acute MI, Thyrotoxicosis, Adrenal insufficiency, inability to swallow caps None **Weight reduction**
Thyroid Product Armour Thyroid (Rx) levothyroxine/liothyronine (Y) Hypothyroidism: daily tab Beef/Pork allergy, Thyrotoxicosis, Adrenal insufficiency None **Weight reduction**
Thyroid Product Cytomel (Rx) liothyronine (Y) Hypothyroidism, Suppression test, Myxedema, Goiter: daily tab Adrenal insufficiency, MI or thyrotoxicosis None **Weight reduction**
Vaccine, Inactivated Prevnar 13 (Rx) pneumococcal conjugate vaccine (N) Pneumonia Px: once IM susp Diphtheria toxoid allergy Chills Skin rash Pain/red/swelling/tenderness at inj site Arthralgia Fever None
Vaccine, Inactivated Pneumovax 23 (Rx) pneumococcal polysaccharide vaccine (N) Pneumonia Px: once IM/SQ susp None None None
Vaccine, Live Varivax (Rx) varicella vaccine (N) Varicella Px: 2 doses separated by at least 4 weeks SQ inj Neomycin or gelatin allergy, Immunosuppressed, Active TB, Febrile, Pregnancy Inj site rxn Fever None
Vaccine, Live Zostavax (Rx) zoster vaccine (N) HVZ (shingles) PX: once SQ soln Neomycin or gelatin allergy, Immunosuppressed, Pregnancy Pain/red/swelling/itching at inj site None
Created by: kcapizzi
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