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ANS Drugs
These drugs affect the Autonomic Nervous System
| Drug Name | Drug Classification | Trade Name | Used to Treat |
|---|---|---|---|
| Carbamylcholine | Direct-Acting Cholinergic | N/A | Atony of the GI tract and to stimulate uterine contractions in swine |
| Bethanechol | Direct-Acting Cholinergic | Urecholine | GI and urinary tract atony |
| Pilocarpine | Direct-Acting Cholinergic | Isopto Carpine, Akarpine, Pilocar | Reduces intraocular pressure associated with glaucoma |
| Metoclopramide | Direct-Acting Cholinergic | Reglan | Control vomiting and to promote gastric tract emptying |
| Edrophonium | Indirect-Acting Cholinergic | Tensilon | Diagnose myasthenia gravis |
| Neostigmine | Indirect-Acting Cholinergic | Prostigmine, Stiglyn | Urine retention, GI atony, and used as antidote to neuromuscular blocking agents |
| Physostigmine | Indirect-Acting Cholinergic | Antilirium, Eserine | Urine retention, GI atony, and used as antidote to neuromuscular blocking agents |
| Organophosphate compounds | Indirect-Acting Cholinergic | N/A | Used as insecticide dips |
| Demecarium | Indirect-Acting Cholinergic | Humorsol | Preventive management of glaucoma |
| Pyridostigmine | Indirect-Acting Cholinergic | Mestinon | Treatment of myasthenia gravis |
| Atropine | Cholinergic Blocking Agent | Numerous generic/trade names available for parenteral or opthalmic administration | Preanesthetic, counteract organophosphate poisoning, dilate pupils for opthalmic exam, control ciliary spasms of eye, treat bradycardia, slow hypermotile gut |
| Methscopolamine | Cholinergic Blocking Agent | Biosol-M | Control diarrhea |
| Glycopyrrolate | Cholinergic Blocking Agent | Robinul-V | Similar to atropine (longer duration of action), primarily used as preanesthetic |
| Aminopentamide | Cholinergic Blocking Agent | Centrine | Control vomiting and diarrhea in dogs and cats |
| Propantheline | Cholinergic Blocking Agent | Pro-Banthine | Diarrhea, urinary incontinece, bradycardia; also used to reduce colonic peristalsis in horses to allow rectal exam |
| Pralidoxime | Cholinergic Blocking Agent | Protopam, 2-PAM | Organophosphate intoxication |
| Epinephrine | Adrenergic Agent | Adrenalin | Stimulates all receptors to cause increase in HR and CO, constriction of blood vessels in skin, dilation of blood vessels in muscle dilation of bronchioles, increase of metabolic rate |
| Norepinephrine | Adrenergic Agent | Levophed | Vasopressor (raise blood pressure) |
| Isoproterenol | Adrenergic Agent | Isuprel | Bronchodilation |
| Phenylephrine | Adrenergic Agent | Neo-Synephrine | Nasal vasoconstrictor |
| Dopamine | Adrenergic Agent | Intropin | Shock, congestive heart failure, increase renal perfusion |
| Phenylpropanolamine | Adrenergic Agent | Proin | Urinary incontinence in dogs |
| Dobutamine | Adrenergic Agent | Dobutrex | Short-term treatment of heart failure |
| Albuterol | Adrenergic Agent | Proventil | Bronchodilation |
| Phenoxybenzamine | Adrenergic Blocking Agent (Alpha Blocker) | Dibenyline | Hypotensive (vasodilator) agent |
| Aacepromazine | Adrenergic Blocking Agent (Alpha Blocker) | Ace | Tranquilizer; vasodilation |
| Prazosin | Adrenergic Blocking Agent (Alpha Blocker) | Minipress | Hypotensive agent |
| Yohimbine | Adrenergic Blocking Agent (Alpha Blocker) | Yobine | Antidote for xylazine toxicity |
| Atipamezole | Adrenergic Blocking Agent (Alpha Blocker) | Antisedan | Reversal agent for dexmedetomidine |
| Propranolol | Adrenergic Blocking Agent (Beta Blocker) | Inderal | Cardiac arrythmias and hypertrophic cardiomyopathy |
| Timolol | Adrenergic Blocking Agent (Beta Blocker) | Timoptic | Opthalmic preparation to treat glaucoma |
| Atenolol | Adrenergic Blocking Agent (Beta Blocker) | Tenormin | Cardiac arrythmias and hypertrophic cardiomyopathy |
| Carteolol | Adrenergic Blocking Agent (Beta Blocker) | Ocupress | Human labeled antiglaucoma medication |
| Levobunolol | Adrenergic Blocking Agent (Beta Blocker) | Betagan | Human labeled antiglaucoma medication |
| Metipranolol | Adrenergic Blocking Agent (Beta Blocker) | OptiPranolol | Human labeled antiglaucoma medication |
| Acetylcholine | Direct-Acting Cholinergic | N/A | seldom used clinically because it is rapidly broken down by acetylcholinesterase |