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ANS Drugs

These drugs affect the Autonomic Nervous System

Drug NameDrug ClassificationTrade NameUsed to Treat
Carbamylcholine Direct-Acting Cholinergic N/A Atony of the GI tract and to stimulate uterine contractions in swine
Bethanechol Direct-Acting Cholinergic Urecholine GI and urinary tract atony
Pilocarpine Direct-Acting Cholinergic Isopto Carpine, Akarpine, Pilocar Reduces intraocular pressure associated with glaucoma
Metoclopramide Direct-Acting Cholinergic Reglan Control vomiting and to promote gastric tract emptying
Edrophonium Indirect-Acting Cholinergic Tensilon Diagnose myasthenia gravis
Neostigmine Indirect-Acting Cholinergic Prostigmine, Stiglyn Urine retention, GI atony, and used as antidote to neuromuscular blocking agents
Physostigmine Indirect-Acting Cholinergic Antilirium, Eserine Urine retention, GI atony, and used as antidote to neuromuscular blocking agents
Organophosphate compounds Indirect-Acting Cholinergic N/A Used as insecticide dips
Demecarium Indirect-Acting Cholinergic Humorsol Preventive management of glaucoma
Pyridostigmine Indirect-Acting Cholinergic Mestinon Treatment of myasthenia gravis
Atropine Cholinergic Blocking Agent Numerous generic/trade names available for parenteral or opthalmic administration Preanesthetic, counteract organophosphate poisoning, dilate pupils for opthalmic exam, control ciliary spasms of eye, treat bradycardia, slow hypermotile gut
Methscopolamine Cholinergic Blocking Agent Biosol-M Control diarrhea
Glycopyrrolate Cholinergic Blocking Agent Robinul-V Similar to atropine (longer duration of action), primarily used as preanesthetic
Aminopentamide Cholinergic Blocking Agent Centrine Control vomiting and diarrhea in dogs and cats
Propantheline Cholinergic Blocking Agent Pro-Banthine Diarrhea, urinary incontinece, bradycardia; also used to reduce colonic peristalsis in horses to allow rectal exam
Pralidoxime Cholinergic Blocking Agent Protopam, 2-PAM Organophosphate intoxication
Epinephrine Adrenergic Agent Adrenalin Stimulates all receptors to cause increase in HR and CO, constriction of blood vessels in skin, dilation of blood vessels in muscle dilation of bronchioles, increase of metabolic rate
Norepinephrine Adrenergic Agent Levophed Vasopressor (raise blood pressure)
Isoproterenol Adrenergic Agent Isuprel Bronchodilation
Phenylephrine Adrenergic Agent Neo-Synephrine Nasal vasoconstrictor
Dopamine Adrenergic Agent Intropin Shock, congestive heart failure, increase renal perfusion
Phenylpropanolamine Adrenergic Agent Proin Urinary incontinence in dogs
Dobutamine Adrenergic Agent Dobutrex Short-term treatment of heart failure
Albuterol Adrenergic Agent Proventil Bronchodilation
Phenoxybenzamine Adrenergic Blocking Agent (Alpha Blocker) Dibenyline Hypotensive (vasodilator) agent
Aacepromazine Adrenergic Blocking Agent (Alpha Blocker) Ace Tranquilizer; vasodilation
Prazosin Adrenergic Blocking Agent (Alpha Blocker) Minipress Hypotensive agent
Yohimbine Adrenergic Blocking Agent (Alpha Blocker) Yobine Antidote for xylazine toxicity
Atipamezole Adrenergic Blocking Agent (Alpha Blocker) Antisedan Reversal agent for dexmedetomidine
Propranolol Adrenergic Blocking Agent (Beta Blocker) Inderal Cardiac arrythmias and hypertrophic cardiomyopathy
Timolol Adrenergic Blocking Agent (Beta Blocker) Timoptic Opthalmic preparation to treat glaucoma
Atenolol Adrenergic Blocking Agent (Beta Blocker) Tenormin Cardiac arrythmias and hypertrophic cardiomyopathy
Carteolol Adrenergic Blocking Agent (Beta Blocker) Ocupress Human labeled antiglaucoma medication
Levobunolol Adrenergic Blocking Agent (Beta Blocker) Betagan Human labeled antiglaucoma medication
Metipranolol Adrenergic Blocking Agent (Beta Blocker) OptiPranolol Human labeled antiglaucoma medication
Acetylcholine Direct-Acting Cholinergic N/A seldom used clinically because it is rapidly broken down by acetylcholinesterase
Created by: SilverSWolfe