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CLP CH5

TermDefinition
Major Depressive Disorder Sad mood OR loss of pleasure (anhedonia) in usual activities. At least 5 symptoms (counting sad mood and loss of pleasure) Symptoms present nearly every day or most of the day for at least 2 weeks.
MDD: Episodic symptoms tend to dissipate over time
MDD: Recurrent Once depression occurs, future episodes likely
MDD: subclinical depression Sadness plus 3 other symptoms for 10 days Significant impairments in functioning even thought full diagnostic criteria are not met
MDD: Gender differences women are twice as likely as men to experience depression
Seasonal Affective Disorder (SAD) Experiences depression during two consecutive winters and symptoms clear during the summer Related to changes in levels of melatonin
What factors contribute to onset of mood disorders? Neurobiological factors Psychosocial factors
Overactivity of HPA axis Triggers release of cortisol, stress hormone
Findings that link depression to high cortisol levels Cushing’s syndrome Causes oversecretion of cortisol Symptoms include those of depression
Neuroticism Tendency to react with higher levels of negative affect predicts onset of depression
Negative triad negative view of self, world, future
Negative schema underlying tendency to see the world negatively
Negative schema cause cognitive biases tendency to process information in negative ways
Hopelessness Theory Most important trigger of depression is hopelessness Desirable outcomes will not occur Person has no ability to change situation
Attributional Style The explanations a person forms about why a stressor has occurred
Rumination Theory A specific way of thinking: tendency to repetitively dwell on sad thoughts (Nolen-Hoeksema, 1991)
Triggers of depressive episodes Negative life events, neuroticism, negative cognitions, expressed emotion, and lack of social support
Predictors of Mania Reward sensitivity Sleep disruption
Interpersonal psychotherapy (IPT) Short-term psychodynamic therapy Focus on current relationships
Cognitive therapy Monitor and identify automatic thoughts Replace negative thoughts with more neutral or positive thoughts
Mindfulness-based cognitive therapy (MBCT) Strategies, including meditation, to prevent relapse
Behavioral activation (BA) therapy Increase participation in positively reinforcing activities to disrupt spiral of depression, withdrawal, and avoidance
Behavioral couples therapy Enhance communication and satisfaction
Psychoeducational approaches Provide information about symptoms, course, triggers, and treatments
Cognitive Therapy (CT) Draws on same techniques that are used in Major Depressive Disorder
Family-focused treatment (FFT) Educate family about disorder, enhance family communication, improve problem solving
STAR-D Attempted to evaluate effectiveness of antidepressants in real-world settings
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