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Summer PDA VT

Generic NameMOATherapeutic Use
Carbachol non selective N and M agonist (not susceptible to AchE) topical tx of glaucoma
Pilocarpine M agonist xerostomia (dry mouth)
Demecarium long acting AchE inhibitor open angle glaucoma
Donepezil Oral AchE inhibitor; reversible; greater affinity for brain AchE than periph AchE Alzheimer's
Echothiophate long acting AchE inhibitor; organophosphate (wont be hydrolyzed) open angle glaucoma
Edrophonium AchE inhibitor OH binds reversibly to active site-lasts 2-10 min diagnosing Myasthenia Gravis
Physostigmine AchE inhibitor (lipophilic and will penetrate the CNS) tx CNS effects of anticholinergic over dose; drug poisoning
Atropine non selective muscarinic blocker tachycardia (brady at low doses), mydriasis, inhibit excessive salvation and mucus secretion during surgery, prevent vagal reflexes induced by surgery trauma, and counteract the muscarinic poison effects of certain mushrooms
Darifenacin selective M3 blocker tx of overactive bladder
Flavoxate anti M urinary bladder spasms
Hyoscyamine anti M (cousin to atropine) tx of GI problems; some parkinsons symptoms
Ipratropium M antagonist; cant cross BBB tx of COPD (asthma)
Scopolamine M antagonist; can cross BBB motion sickness; nausea and vomiting
Solifenacin selective M3 blocker tx of over active bladder
Tiotropium M antagonist like ipratropium but causes greater bronchodilation to treat COPD
Tolterodine anti M tx of overactive bladder
Trimethaphan N receptor antagonist (causes ganglia block) tx of HTN crisis in pts with acute aortic dissection
Tubocurarine long acting N antagonist (prefers Nm); reversed by AchE inhibitor induction of neuromuscular blockade in surgery; intubation
pyridostigmine ache inhibitor orthostatic HTN, mysthenia gravis
Bethanechol selective M3 agonist (not susceptible to AchE) promote GI and bladder motility
Created by: kbacke
Popular Pharmacology sets

 

 



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